ID A0A0X8G4A9_9FLAO Unreviewed; 844 AA.
AC A0A0X8G4A9;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Clp protease ClpC {ECO:0000313|EMBL:AMC09785.1};
GN ORFNames=Lupro_00235 {ECO:0000313|EMBL:AMC09785.1};
OS Lutibacter profundi.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Lutibacter.
OX NCBI_TaxID=1622118 {ECO:0000313|EMBL:AMC09785.1, ECO:0000313|Proteomes:UP000059672};
RN [1] {ECO:0000313|Proteomes:UP000059672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LP1 {ECO:0000313|Proteomes:UP000059672};
RA Wissuwa J., Le Moine Bauer S., Stokke R., Dahle H., Steen I.H.;
RT "Complete genome sequence of Lutibacter profundus strain LP1.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AMC09785.1, ECO:0000313|Proteomes:UP000059672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LP1 {ECO:0000313|EMBL:AMC09785.1,
RC ECO:0000313|Proteomes:UP000059672};
RX PubMed=27118569; DOI=10.1099/ijsem.0.001105;
RA Le Moine Bauer S., Roalkvam I., Steen I.H., Dahle H.;
RT "Lutibacter profundi sp. nov., isolated from a deep-sea hydrothermal system
RT on the Arctic Mid-Ocean Ridge and emended description of the genus
RT Lutibacter.";
RL Int. J. Syst. Evol. Microbiol. 66:2671-2677(2016).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP013355; AMC09785.1; -; Genomic_DNA.
DR RefSeq; WP_068205503.1; NZ_CP013355.1.
DR AlphaFoldDB; A0A0X8G4A9; -.
DR STRING; 1622118.Lupro_00235; -.
DR KEGG; lut:Lupro_00235; -.
DR PATRIC; fig|1622118.3.peg.50; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000059672; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:AMC09785.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:AMC09785.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000059672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..148
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 444..479
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 155..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 94864 MW; FC9C64FE27C25D13 CRC64;
MDDNFSPKVK DVITYSKEEA IRLGHDFIGT EHLMLGLLRK GDGKAIEILN SLEINLEHLR
KKIEVLSPAN FSIDLSKEKK SIHLTRQAEK ALKTTFLEAK LYQNDAVNTA HLLLCILRNE
NDPTTKLLHN FGVSYNDAKT VFKQLFSDQE LDLPKAENTS DDDFDTPKQN PFEQSKSNKP
SDKKSKTPVL DNFGRDLTRL AEEGKLDPVV GRKKEIERVS QILSRRKKNN PMLIGEPGVG
KSAIAEGLAL RIIERKVSRI LFNKRIVSLD LASLVAGTKY RGQFEERMKA LMNELEKNDD
IILFIDEIHT IVGAGGATGS LDASNMLKPA LARGEIQCIG ATTLDEFRTN IEKDGALERR
FQKIIVEPTS VDETIQILQN IKNKYEEHHN VDYTDEAIVA CVKLTNRYMT DRFLPDKAID
AMDEAGSRIH ITNIVVPKEV LNLEAQLEKV KEDKSAAVNG QKYEEAARLR DDEKRIENLL
LTEQIKWEEA SKLNREVVTQ DNVAEVVSMM TGIPVNRVAE AESKRLHDLP KLIKGKVIGQ
NEAVSKVVKA IQRNRVGLKD PNKPIGSFIF LGQTGVGKTQ LAKVLATELF DSEDALVRID
MSEYMEKFAI SRLIGAPPGY VGYEEGGQLT EKIRRKPYAV VLLDEIEKAH PDVFNMLLQI
LDDGFITDSL GRRIDFRNTI IIMTSNIGSR QLKDFGAGVG FGTAAKASQA NAHAKSVIEN
ALKKSFAPEF LNRIDDVVVF NALEREDIHS IIDIELSKLI ERIEDIGYNL QLTEEAKDYI
ADKGFDKQYG ARPLKRAIQK YIEDTLAEEI VNSKLNEGDS IFMDLDKEKN ELTIKISKGK
KKVE
//
