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Database: UniProt
Entry: A0A0X8G4Y2_9FLAO
LinkDB: A0A0X8G4Y2_9FLAO
Original site: A0A0X8G4Y2_9FLAO 
ID   A0A0X8G4Y2_9FLAO        Unreviewed;       475 AA.
AC   A0A0X8G4Y2;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   25-OCT-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Lupro_00005 {ECO:0000313|EMBL:AMC09743.1};
OS   Lutibacter profundi.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Lutibacter.
OX   NCBI_TaxID=1622118 {ECO:0000313|EMBL:AMC09743.1, ECO:0000313|Proteomes:UP000059672};
RN   [1] {ECO:0000313|EMBL:AMC09743.1, ECO:0000313|Proteomes:UP000059672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LP1 {ECO:0000313|EMBL:AMC09743.1,
RC   ECO:0000313|Proteomes:UP000059672};
RA   Wissuwa J., Le Moine Bauer S., Stokke R., Dahle H., Steen I.H.;
RT   "Complete genome sequence of Lutibacter profundus strain LP1.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013355; AMC09743.1; -; Genomic_DNA.
DR   RefSeq; WP_068205452.1; NZ_CP013355.1.
DR   EnsemblBacteria; AMC09743; AMC09743; Lupro_00005.
DR   KEGG; lut:Lupro_00005; -.
DR   PATRIC; fig|1622118.3.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000059672; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000059672};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059672}.
FT   DOMAIN      172    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  54547 MW;  BD6C2B9FAF1362E8 CRC64;
     MTKTASSVWG ECLSFIEDNI KQQAYKTWFE PIKPMKLSGE ALTIQVPSKF FYEWLEEHYI
     KLLRVALVKQ LGEDAKLIYD VRMENNYSSS KQHTLKIPSS NRNPINAQGI TVPLDFNKRE
     LKNPFVIPGI QKVKIESQLN PNYNFESFIE GDSNRLARSA SMAVANKPGG TSFNPLLIYG
     GVGLGKTHLA HAIGVQIKDK YPDKTVLYIS SEKFTQQYID SVKGNTRNDF IHFYQMIDVL
     IIDDVQFLSG KTGTQDVFFH IFNHLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA
     ELQVPDYETR VLILQNKLYR DGVEMPEEIV EYIAKYIKSN VRELEGVLIS MIAQASFNRK
     EFTLALTKQI VDKFVKNTKR EVSIDYIQKI VSNYFELDVA TLQSKTRKRH IVQARQLAMY
     FAKRMTKASL ASIGSQIGKR DHATVLHACK TVDNLTETDK QFRRYVDDLT KKLTF
//
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