ID A0A0X8GJL7_9BURK Unreviewed; 752 AA.
AC A0A0X8GJL7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=VN23_01820 {ECO:0000313|EMBL:AMC33428.1};
OS Janthinobacterium sp. B9-8.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=1236179 {ECO:0000313|EMBL:AMC33428.1, ECO:0000313|Proteomes:UP000069577};
RN [1] {ECO:0000313|EMBL:AMC33428.1, ECO:0000313|Proteomes:UP000069577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B9-8 {ECO:0000313|EMBL:AMC33428.1,
RC ECO:0000313|Proteomes:UP000069577};
RA Xu X., Jin W., Wu Q., Jiang L., Huang H.;
RT "The whole genome sequence of Janthinbacterium sp. B9-8, a bacterium
RT isolated from low temperature sewage.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP014222; AMC33428.1; -; Genomic_DNA.
DR RefSeq; WP_046353468.1; NZ_CP014222.1.
DR AlphaFoldDB; A0A0X8GJL7; -.
DR STRING; 1236179.VN23_01820; -.
DR KEGG; jab:VN23_01820; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000069577; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 508..697
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 752 AA; 82649 MW; D6CB6436ED34719E CRC64;
MLIAYLLLIA SFICGVCLLQ AQPGLPLLWP ALSIAALFFL LSRWRLPQLF LMLSLLALGF
SWANWRAQIR MADRLNPVLE QQVIEITGFV SDLPQASRFG TRFLFKPDAT NTRLPGKIQL
QWYGQADRVK AGEHWRFLVK LKQVHVQSNP GGFDLESWFL QQDIGATGTV KSGVLLAEKS
AGLHRIRAHL RDRIHHALPD APYRGVIIAL TVGDQGGILP EQWQRFAATG VTHLISISGL
HITLLAAMAA ATCNGLWRRI PLLAARFAAQ RAALIAGVIT AFCYCLLAGM AIPTQRTLFM
LSIAAICLWR AQASAISAIW AAALLVTVVI DPFAVLSIGF WLSYLTVGAL LWAGSNQLGK
SAKWKTWVSS QAAATLASAP VLLVVFGQLP LVSPLANAFA IPIVSILITP LALAGLLDPS
GYLLYGAERL FAATDYLLQW CTALPTIAFN MPGPITLLPA AFGVMLLLLP RGIPARRLGL
ICCLPLFISS SGSIQPGQYR ATVLDVGQGL AVLVQTAQHQ LLFDTGQLPN GERVLLPALR
SARIRQLDAL ILSHNDNDHI GAAEPLLKNM PSPLIWHSLP DDHPLWANQK AKRQRCQTGT
TWVWDKVRFR FIWPNEQNTA RSDNAQSCVL LIDNGQHRLL IPADIGKHEE ARLIEQGLGQ
IDILLVPHHG SKTSSSILFV KQTSPQYAIY SAAYLNHFGH PKPEITARYA AAQAQNLRTD
QTGALIFDVG EKIKLTRWRH AHPHYWHQPT GH
//
