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Database: UniProt
Entry: A0A0X8JPQ0_9DELT
LinkDB: A0A0X8JPQ0_9DELT
Original site: A0A0X8JPQ0_9DELT 
ID   A0A0X8JPQ0_9DELT        Unreviewed;       428 AA.
AC   A0A0X8JPQ0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   25-OCT-2017, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   ORFNames=AXF15_05310 {ECO:0000313|EMBL:AMD92587.1};
OS   Desulfomicrobium orale DSM 12838.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfomicrobiaceae; Desulfomicrobium.
OX   NCBI_TaxID=888061 {ECO:0000313|EMBL:AMD92587.1, ECO:0000313|Proteomes:UP000063964};
RN   [1] {ECO:0000313|EMBL:AMD92587.1, ECO:0000313|Proteomes:UP000063964}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12838 {ECO:0000313|EMBL:AMD92587.1,
RC   ECO:0000313|Proteomes:UP000063964};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00747914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP014230; AMD92587.1; -; Genomic_DNA.
DR   EnsemblBacteria; AMD92587; AMD92587; AXF15_05310.
DR   KEGG; doa:AXF15_05310; -.
DR   KO; K02313; -.
DR   Proteomes; UP000063964; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000063964};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000063964}.
FT   DOMAIN      128    249       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      331    400       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   428 AA;  48758 MW;  26CB05F5D8758F66 CRC64;
     MDTDRIHEAL LREFSAGEME KWRPALRMAV EDGVLTVHFP HRFFAQWFAA HVRPRFERAL
     AGVIPVTYEK GSVRPSDSFP EPPPFFQTPG ETDLPFGSRF TFENFLANNK NHFPLASARE
     VAQNTEAKYN PFVLCGESGS GKSFLLRAMA NARAGTAGGT VRLTGIEDMH KLYSSRSDAR
     DVLLSADFLA VDDLQDIARH QHLQNELVAL FDAFHLRRRQ MVFACSGKVA RFAFLHQKLK
     SRLEWGLIVT LKAPDLDIRM RFIQNRCKER GLDLSKDRIL LLAQRFGDLR NLEGCLLKLW
     AYHELVRERI SDQDFENILS HLDTRAATPL TPEQIMDEVC ASFGVTREDL LSPGRRHELV
     LARQAGMFLC RKHLGLSFPE LGRIFGGRDH STALYSCKKI EQLQRDDKEI KNRLHDLSGR
     CLALGRDA
//
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