ID   A0A100VY50_9MYCO        Unreviewed;       844 AA.
AC   A0A100VY50;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:GAS88056.1};
GN   ORFNames=RMCB_2152 {ECO:0000313|EMBL:GAS88056.1};
OS   Mycolicibacterium brisbanense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=146020 {ECO:0000313|EMBL:GAS88056.1, ECO:0000313|Proteomes:UP000069620};
RN   [1] {ECO:0000313|EMBL:GAS88056.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM15654 {ECO:0000313|EMBL:GAS88056.1};
RA   Katahira K., Ogura Y., Gotoh Y., Hayashi T.;
RT   "Draft Genome Sequences of Five Rapidly Growing Mycobacterium Species, M.
RT   thermoresistibile, M. fortuitum subsp. acetamidolyticum, M. canariasense,
RT   M. brisbanense, and M. novocastrense.";
RL   Genome Announc. 4:e00322-16(2016).
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|ARBA:ARBA00008708}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAS88056.1}.
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DR   EMBL; BCSX01000021; GAS88056.1; -; Genomic_DNA.
DR   RefSeq; WP_062828767.1; NZ_JACKTM010000057.1.
DR   AlphaFoldDB; A0A100VY50; -.
DR   STRING; 146020.RMCB_2152; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000069620; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17921; DEXHc_Ski2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR021904; DUF3516.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF12029; DUF3516; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:GAS88056.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          48..204
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          228..413
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   844 AA;  92894 MW;  F713B3991CC744FE CRC64;
     MPTALLDDPG DLSALRARSA DPDTLFTDFA AWAEANGTAL YPAQEEALIE LVSGANVVLA
     TPTGSGKSLV ATGALYATLA AGKRSYYTAP IKALVSEKFF ALCDVFGAVN VGMLTGDAAV
     NSDAPIIACT AEVLANIALR EGAQADIGLV VMDEFHFYGD PDRGWAWQVP LLELPRAQFL
     LMSATLGDVT FLREDLTRRT GRPTALVAGA ERPVPLFYSY ATTPMHETIQ DLLDTKQAPV
     YVVHFTQASA LERAQALMSV NVSTKDEKAA IAEAIGGFRF TSAFGSTLSR LVRHGIGVHH
     AGMLPKYRRL VEQLAQAGLL KVICGTDTLG VGINVPIRTV VFSALSKYDG TRTRLLSARE
     FHQIAGRAGR AGYDTVGTVV VQAPDHEVEN LKQFAKVADD PKKRRKLVRR KVPEGMVPWS
     EATMNRLVSA APEALTSNMR VSTAMILDVV DRPGDPFVAM RRLLTDNHEP RKRQLRHIRE
     AVGIARSLLQ AGVLERLDEP EPDGRRYRLT VDLPPDFALN QPLSTFALAA IDLLDPESET
     YALDVVSVIE ATLEDPRQIL AAQLNKARGE AVAQMKADGI EYEERIELLD EVSYPKPLEE
     LLNHAFDVYL RTNPWAADGR LSPKSIVREM WERAMTFREF VSAYGLTRSE GAVLRYLSDA
     FKALRSGVPA AARTDEVIDI VEWIGELVRQ VDSSLLDEWE QLTDPDQPHD VPVATPTRPR
     PLTGNERAFT AMVRNALFRR VELFARRRWD ELGELDGDAG WSAQRWEEVG LEYFAEHSDL
     GTGADARGPA MLIFDRQPGV WRVRQILDDP AGDRDWGFDV EVDLEESDEA GTAVLRLVDA
     GRMD
//