ID A0A101HIT2_9BACT Unreviewed; 424 AA.
AC A0A101HIT2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE SubName: Full=VI polysaccharide biosynthesis protein {ECO:0000313|EMBL:KUK77628.1};
GN ORFNames=XD93_0198 {ECO:0000313|EMBL:KUK77628.1};
OS candidate division WS6 bacterium 34_10.
OC Bacteria; Candidatus Dojkabacteria.
OX NCBI_TaxID=1641389 {ECO:0000313|EMBL:KUK77628.1, ECO:0000313|Proteomes:UP000053904};
RN [1] {ECO:0000313|Proteomes:UP000053904}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK77628.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGGO01000017; KUK77628.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101HIT2; -.
DR PATRIC; fig|1641389.3.peg.269; -.
DR Proteomes; UP000053904; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 317..409
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 424 AA; 46968 MW; BF8A33A738EBB815 CRC64;
MQKVSIIGLG YVGLPLALAI EKSGKYEVVG FDISETQVKK IKDKECPITD EIAEKELKEL
DLHATTDEKE IKGSDYYIIC VPTPVLDDYT PDYTPVKSAG ETVSKYLEKG QTVVLESTVN
PGTCEEILLP ILEAGSGLKA GKDFNIAMCP ERINPGDPKW NVYNIPRNIG SLVPEKTKEV
ADFYRSFLEG NINEVSSLKI AEATKIVENA FRDINIAYVN ELAKSFDAMG IDLIETLKGS
SNKPFSFMVH WPGRGVGGHC IAVDPYYLIN RAAESGFDHK LLKMAREVNN SMPEYTVERL
QEALNEVKLP INGTKIALLG LSYKEDIADL RESPCLEILE ILEKKGADLL VFDPFVPDMS
NVESLDEALD KCDAVIVATA HKKFGDLTEK IGKRKNVKVV VDGMNKLDKE EIEKEGKIYR
GIGK
//
