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Database: UniProt
Entry: A0A101HN07_9BACT
LinkDB: A0A101HN07_9BACT
Original site: A0A101HN07_9BACT 
ID   A0A101HN07_9BACT        Unreviewed;       520 AA.
AC   A0A101HN07;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-SEP-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=XD95_0053 {ECO:0000313|EMBL:KUK79877.1};
OS   Microgenomates bacterium 39_7.
OC   Bacteria; Candidatus Microgenomates.
OX   NCBI_TaxID=1641390 {ECO:0000313|EMBL:KUK79877.1, ECO:0000313|Proteomes:UP000054437};
RN   [1] {ECO:0000313|EMBL:KUK79877.1, ECO:0000313|Proteomes:UP000054437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=39_7 {ECO:0000313|EMBL:KUK79877.1};
RA   Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA   Andersen G.L., Banfield J.F.;
RT   "Genome-resolved metagenomic analysis reveals roles for candidate
RT   phyla and other microbial community members in biogeochemical
RT   transformations in oil reservoirs.";
RL   MBio 7:e01669-15(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUK79877.1}.
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DR   EMBL; LGGQ01000003; KUK79877.1; -; Genomic_DNA.
DR   PATRIC; fig|1641390.4.peg.520; -.
DR   Proteomes; UP000054437; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054437};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054437}.
FT   DOMAIN      212    340       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      425    494       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     220    227       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   520 AA;  58241 MW;  B91A836360BFC338 CRC64;
     MSTQTLSQEE VKLIWSQVKE ELKLKISPAA FNTWVLLNPL TTIEVIDQTK ARGTISSPSA
     FHATNLKKNL YSHLKTSIEN VIKKKVELDI RVSDPASVLA SQKQMFGSSN KDNWGWGGSK
     SGVTTANNES HSRQPTYSNG FYGNGSNKVG SPTVEELFSQ SNIQSSSFDR TLSAVRQAGL
     KMDYQFESFA VSGSNEMAHA AATAVAKRPG EAYNPLFFYG GVGVGKTHLM QAIGHYILKQ
     DPGLKVIYCT GEEFTNDIID AIRNKKATTF KKKFRSAHTL LIDDIQFIGG KNAVQEEFFH
     TFNALTKLSS QIVLTSDRPP SEINLLEDRL KSRFEAGLMV DIQQPSAELK TAIVLIKAKS
     SGLSMPIKLA EQIASRVDGA RKIEGVIATI RSEVELKKKE MDEELITSIL EKEKNDSKDK
     RIKLRPQKVI KKVSSYYQIN QTALKGKRRN KEIVEARHMA MFILKNDLEM SYVDIGKWFS
     NRDHTSVMHA KDKIEQLIKE DVSVQEDYHK IKGELVNISR
//
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