ID A0A101JN47_9ACTN Unreviewed; 803 AA.
AC A0A101JN47;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:KUL29881.1};
GN ORFNames=ADL15_26430 {ECO:0000313|EMBL:KUL29881.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL29881.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL29881.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL29881.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL29881.1}.
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DR EMBL; LLZH01000275; KUL29881.1; -; Genomic_DNA.
DR RefSeq; WP_067696746.1; NZ_LLZH01000275.1.
DR AlphaFoldDB; A0A101JN47; -.
DR OrthoDB; 3304401at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 181..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..256
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 320..371
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 403..535
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 544..800
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 803 AA; 87115 MW; F2AEBF43A2D4B2A9 CRC64;
MNVRQKLLAG YLVVALLVVA TALTAWLTDA ASARRAAALE AAQVARGIGK DIALGLPVDT
PGEVITPLYD HRAALTNFIN RLHDNQRRDI VVVDTTKYIL GDALIENIGS VFDHDTGDEV
GRTIADGRSR VFVEQSVDYP QGIKQVVVQM TRASGVVVGA VILEYTPLYE QMLAGTRQAQ
IIILCTGSVA FLSVLLIGFL LATSLTRRIT ALTTAVRVIR TGDYSHRVPV TGGRDEIGRL
AGAFNAMAGE LDRSAREILA KEYTDSILAN AGEGICGLDT TGRIAFANAA AGRITGLGVA
GLLDRDAAEV LPETAGLTAA TREGRLQRAD GTSVTVEYTV NAIEKDGRTI GAVILLRDVT
RQHALEYDLR HQALHDGLTG LPNRKLLLDR LEHALTRSRA ASEPLAVLYL DLDGFKRVND
SLGHNAGDLL LRTAAERLTG VLRAQDTVAR LGGDEFAVLL ENAVPEAVER VAQDCLDALA
RPFLIHNREV LVTVSIGVVP DAARYTSADE VLRNADVAMY AAKDQGKNRF LTFENRMHEQ
LLSRLDQESR LRDAVHRGEL RMHLQPVVSV PDGQMVGAEA LVRWQDPQHG LRQPGSFIPL
AEETGMIVEI DRWVLMEACR TIKQWQDDDP ATAPAWVSVN LSAAHLEVPD LTDRIAYALS
TSGLPARCLV LELTETILMR DIAVTAARLE ELRELGVKIA IDDFGTGYSS LGYLRDIPVD
VLKIDRSFIT GMTGNGRQQE LVNAVIQLGH MLGLRVVVEG IEEADQLALL SVMGCKFVQG
YHLGRPVPAD ELRVLRAAPA VLA
//
