ID   A0A101NNB3_9ACTN        Unreviewed;      1247 AA.
AC   A0A101NNB3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:KUM96164.1};
GN   ORFNames=AQI88_13475 {ECO:0000313|EMBL:KUM96164.1};
OS   Streptomyces cellostaticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM96164.1, ECO:0000313|Proteomes:UP000054241};
RN   [1] {ECO:0000313|EMBL:KUM96164.1, ECO:0000313|Proteomes:UP000054241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM96164.1,
RC   ECO:0000313|Proteomes:UP000054241};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT   for the species Streptomyces cellostaticus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM96164.1}.
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DR   EMBL; LMWL01000023; KUM96164.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101NNB3; -.
DR   STRING; 67285.AQI88_13475; -.
DR   OrthoDB; 9804511at2; -.
DR   Proteomes; UP000054241; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF43; PUTATIVE SUBFAMILY (AFU_ORTHOLOGUE AFUA_6G13760)-RELATED; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT   DOMAIN          50..179
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
SQ   SEQUENCE   1247 AA;  135198 MW;  18707D4ECB62DF9D CRC64;
     MAVGAQGAAV ALPAKAAAAD REFASSFETG DPAPDWLNTV DTAADGSKRA SGVDGGYTTG
     IPGNATDHVT EVRANGENAG AGEVKENLVD GEPGTKWLTF QPTGWAEFDL DKPIKLMTYA
     LTSANDFDGR DPKDWTLQGS VDGKDWKTVD TRSGESFSER FQTKSYDLAQ PAEYEHFRLE
     VTKNNGAPDI LQIADVQFST GGGGGPVPQD MLSLVDRGPS GSPTAKARAG FTGKRALRYA
     GRHTAAGRAY SYNRVFDVNV KVGGDTELSY RIFPSMADGD RDYDATNVSV DLAFTDGTYL
     SDLGAIDQHG FPLSPRGQGA AKALYVNQWN SVASRIGSVA AGRTVDRILV AYDSPNGPAK
     FRGWIDDIAL RQAAPEKPKA HLSDYALTTR GTNSSGSFSR GNDFPATALP HGFNFWTPVT
     NASSLSWLYE YARANNDDNL PTIQAFSASH EPSPWMGDRQ TFQLMPSAVT GTPDTGRAAR
     QLAFRHENET ARPYYYGVRF ENGLKAEMTP TDHAAVLRFT YPGDDASVLF DNVTEQAGLT
     LDKEHGIVTG YSDVKSGLST GATRLFVYGV FDRPVTDGGS SGVKGYLRFD AGADRTVTLR
     LATSLISIDQ AKDNLGQEIP DGTSFDTVKE RAQRTWDELL GKVEVEGATP DQLTTLYSSM
     YRLYLYPNSG FERVGGKDQY ASPFSPMPGQ DTPTHTGAKI VDGKVYVNNG FWDTYRTTWP
     AYSFLTPSQA GEMVDGFVQQ YKDGGWTSRW SSPGYADLMT GTSSDVAFAD AYVKGVKFDA
     KAAYDAAVKN ATVVPPSSGV GRKGMATSPF LGYTSTDTNE GLSWAMEGYV NDYGIAKMGE
     ALYKKTGDKR YQEESQYFLN RAQDYVDLFD PKAGFFQGRD AQGNWRLDPA KYDPRVWGYD
     YTETNGWGYA FTAPQDSRGL ANLYGGRSGL ADKLDQYFAT PETASPEFVG SYGGVIHEMT
     EARDVRMGMY GHSNQVAHHV IYMYDAAAEP WKAQEYVREA MSRLYTGSEI GQGYHGDEDN
     GEQSAWYLFS ALGFYPLVMG SGEYTIGSPL FKKATVHLEN GRDLVIKAPR NSAQNVYVQG
     VKVNGHPWTS TSLCHALLAK GGVLEFFMGS KPSTWGSGKN AAPVSLTQDD KVPTPRADVL
     KGDGALFDNT SRTSATVTSV DLPVDGAVKP VQYTLTSAAD HTKAPAGWTL QGSTDGTAWT
     TLDHRSGESF PYDRQTRAFT IAAPGSYTKY RLVFDGESTL AEVELLA
//