ID   A0A101NPY4_9ACTN        Unreviewed;       383 AA.
AC   A0A101NPY4;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=PLP-dependent lyase/thiolase {ECO:0000313|EMBL:KUM97226.1};
GN   ORFNames=AQI88_08075 {ECO:0000313|EMBL:KUM97226.1};
OS   Streptomyces cellostaticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM97226.1, ECO:0000313|Proteomes:UP000054241};
RN   [1] {ECO:0000313|EMBL:KUM97226.1, ECO:0000313|Proteomes:UP000054241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM97226.1,
RC   ECO:0000313|Proteomes:UP000054241};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT   for the species Streptomyces cellostaticus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM97226.1}.
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DR   EMBL; LMWL01000011; KUM97226.1; -; Genomic_DNA.
DR   RefSeq; WP_066994194.1; NZ_KQ948017.1.
DR   AlphaFoldDB; A0A101NPY4; -.
DR   STRING; 67285.AQI88_08075; -.
DR   OrthoDB; 34584at2; -.
DR   Proteomes; UP000054241; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.1100; -; 3.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR42937; -; 1.
DR   PANTHER; PTHR42937:SF1; DIAMINOPROPIONATE AMMONIA-LYASE; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:KUM97226.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT   DOMAIN          39..342
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   383 AA;  39155 MW;  6E4512CF305AC9DC CRC64;
     MSDNASSLRT LPWFARPSSR TWRCEPAPAE VRGFHAALPD YAPTPLTELP ALAFELGVGR
     VFVKDESCRL GLPAFKALGA SWAVHRTLAE RAVSGEDPGP VTLVTATDGN HGRAVARTAR
     LLGQHAHVFV PQGVHPQAVT AIVAEQAKVT EVAGAYDEAV RLAAEEAAAP DAVLVQDTAW
     PGYEQIPRWI VEGYSTLCAE IDEQLTAAGA VAGPDLVAVP VGVGSLAQAV VTHYRSRLSE
     GAPALLSVEP EAAACVLESL SAGEPVSVTT GETSMAGLNC GTPSSIAWPY LRGGLDAAVA
     VPDADSARAA ARLAALGVSS GPCGAAALAG LRAVLAGVGA EERRTALGLN ATSVVVLLST
     EGTAANPHST AITEHATPQG SLR
//