ID A0A101NR83_9ACTN Unreviewed; 587 AA.
AC A0A101NR83;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:KUM97888.1};
GN ORFNames=AQI88_05040 {ECO:0000313|EMBL:KUM97888.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM97888.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM97888.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM97888.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM97888.1}.
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DR EMBL; LMWL01000007; KUM97888.1; -; Genomic_DNA.
DR RefSeq; WP_066992488.1; NZ_KQ948016.1.
DR AlphaFoldDB; A0A101NR83; -.
DR STRING; 67285.AQI88_05040; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT DOMAIN 11..328
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 375..476
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 505..563
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 156
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 232
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 587 AA; 64531 MW; C928963F17572F24 CRC64;
MSEFTVAESD FLLDGRPVRL LSGALHYFRV HEGHWRHRLE MLRAMGLNCV ETYVPWNLHQ
PSPGRHRDVQ AVGRFLDAVR AAGLWAIVRP GPYICAEWEN GGLPHWVTGE PGTRARTRDE
RFLFHVRNWF HPLLHEIVPR QIDRGGPVIM VQVENEYGSY GSDTDYLEQL ADLLRVKGVT
VPLFTSDGPE DHMLTGGSLP GVLATVNFGS HARAAFETLR RHRPKGPLMC MEFWCGWFDH
WGGAPVARDP EEAAEALREI LECGASVNLY MAHGGTSFAG WAGANRGGGE LHEGPLEPDV
TSYDYDAPVD EYGRPTEKFW RFREVLARYH PEPVPELPSP PAPLGSPTDV ALTGWAPLVD
VLEALGGEET VTPVPPTFEE LGVGRGLVRY EVGVPGPRQP YPLTVRGLRD LAVVYVDGER
AGVLTEDEPR LKEPVAGPAH VELWVESLGR VNYGPRSGEA KGITGGLLHE RQYLHGVRAR
GLDLDAFADG VEAVPFGASP EDGAPGLYRG TVTVRGAGDA RLELPGWMRG FVWVNGFNLG
RYWSVGPQRS LYVPGPVLRE GENEVWVLEL QEAGPGGGGA TPRLEPV
//
