ID A0A101T6F2_9ACTN Unreviewed; 259 AA.
AC A0A101T6F2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Esterase {ECO:0000313|EMBL:KUN86582.1};
GN ORFNames=AQJ66_11145 {ECO:0000313|EMBL:KUN86582.1};
OS Streptomyces bungoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=285568 {ECO:0000313|EMBL:KUN86582.1, ECO:0000313|Proteomes:UP000053024};
RN [1] {ECO:0000313|EMBL:KUN86582.1, ECO:0000313|Proteomes:UP000053024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41781 {ECO:0000313|EMBL:KUN86582.1,
RC ECO:0000313|Proteomes:UP000053024};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces bungoensis DSM 41781, type strain
RT for the species Streptomyces bungoensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN86582.1}.
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DR EMBL; LMWX01000016; KUN86582.1; -; Genomic_DNA.
DR RefSeq; WP_061919750.1; NZ_KQ948854.1.
DR AlphaFoldDB; A0A101T6F2; -.
DR STRING; 285568.AQJ66_11145; -.
DR OrthoDB; 9786110at2; -.
DR Proteomes; UP000053024; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR012354; Esterase_lipase.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR11614:SF121; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF017388; Esterase_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053024}.
FT DOMAIN 19..229
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT ACT_SITE 93
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 194
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 224
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT BINDING 25
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
FT BINDING 94
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
FT SITE 143
FT /note="Important for substrate specificity"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-3"
SQ SEQUENCE 259 AA; 27955 MW; 18F0AC123F0B1D60 CRC64;
MPVLPGAEPY RHEGGETGVL LCHGFTGSPQ SLRPWAEHHA AHGLTVSLPL LPGHGTRWED
MQVTGWQDWY AEVDRELRLL ADRCSRVFVG GLSMGGALAL RLAARHGERV AGAVVVNPAN
RVHGLSAYAL PVARHLVRTT RGIASDIAKE GAAELGYDRV PLHAAHSLRV FLRRLDGELP
QVTQPLLLLR SARDHVVPAA DSARVLSRIS SVDVTEIVLE QSYHVATLDH DADRIFEESL
AFIGRLAPSV GKEGTAAVG
//
