UniProt: A0A101T7N0

Database: UniProt
Entry: A0A101T7N0_9ACTN

LinkDB:  A0A101T7N0_9ACTN 
Original site:  A0A101T7N0_9ACTN

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Ontology (3)   
   GO (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (5)   
   InterPro (4)   
   Pfam (1)   
All databases (10)   

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ID   A0A101T7N0_9ACTN        Unreviewed;       375 AA.
AC   A0A101T7N0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN   Name=corA {ECO:0000256|RuleBase:RU362010};
GN   ORFNames=AQJ66_10385 {ECO:0000313|EMBL:KUN87348.1};
OS   Streptomyces bungoensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=285568 {ECO:0000313|EMBL:KUN87348.1, ECO:0000313|Proteomes:UP000053024};
RN   [1] {ECO:0000313|EMBL:KUN87348.1, ECO:0000313|Proteomes:UP000053024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 41781 {ECO:0000313|EMBL:KUN87348.1,
RC   ECO:0000313|Proteomes:UP000053024};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces bungoensis DSM 41781, type strain
RT   for the species Streptomyces bungoensis.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates influx of magnesium ions.
CC       {ECO:0000256|RuleBase:RU362010}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUN87348.1}.
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DR   EMBL; LMWX01000014; KUN87348.1; -; Genomic_DNA.
DR   RefSeq; WP_061919489.1; NZ_KQ948854.1.
DR   AlphaFoldDB; A0A101T7N0; -.
DR   STRING; 285568.AQJ66_10385; -.
DR   OrthoDB; 9803416at2; -.
DR   Proteomes; UP000053024; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12830; MtCorA-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   NCBIfam; TIGR00383; corA; 1.
DR   PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU362010};
KW   Ion transport {ECO:0000256|RuleBase:RU362010};
KW   Magnesium {ECO:0000256|RuleBase:RU362010};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053024};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362010};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT   TRANSMEM        318..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
SQ   SEQUENCE   375 AA;  41638 MW;  7503F4E0504A815A CRC64;
     MSMAGSLRKV TGLGGVGGLR KVARLARRRP RVDLNHPARS PLGSSVVNCV TYRDGVRVPG
     CADVVDAVRK VRRSGEGFVW LGLHEPTVGE FAGIAELFDL HPLAVEDAVE AHQRPKLERY
     GDTLFAVFKT VCYVEHERLT ATSEVVDTGE IMVFLGEDFV VTVRHGRHGS LGPLREELEA
     HPRQLAKGPA AVLHAIADHV VDDYLSVTDA VQGDIDQVET DVFSENGART DPGRIYQMKR
     ELLELKRAVV PLSRPVEDLA TRPIRVVDPE IQAYFRDVLD HLLRAKEQIA AFDELLNSIL
     QAHLAQVTVA QNEDMRKITA WAAVIAVPTM VCGVYGMNFD HMPELHWRFG YPLVMGVMAV
     ACLVLYRGFR RNGWL
//

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