ID A0A101T9B5_9ACTN Unreviewed; 649 AA.
AC A0A101T9B5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KUN88092.1};
GN ORFNames=AQJ64_03885 {ECO:0000313|EMBL:KUN88092.1};
OS Streptomyces griseoruber.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1943 {ECO:0000313|EMBL:KUN88092.1, ECO:0000313|Proteomes:UP000052982};
RN [1] {ECO:0000313|EMBL:KUN88092.1, ECO:0000313|Proteomes:UP000052982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40281 {ECO:0000313|EMBL:KUN88092.1,
RC ECO:0000313|Proteomes:UP000052982};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseoruber DSM 40281, type strain
RT for the species Streptomyces griseoruber.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(3+); Xref=ChEBI:CHEBI:29034;
CC Evidence={ECO:0000256|ARBA:ARBA00001965};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN88092.1}.
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DR EMBL; LMWW01000006; KUN88092.1; -; Genomic_DNA.
DR RefSeq; WP_055631509.1; NZ_LIQS01000012.1.
DR AlphaFoldDB; A0A101T9B5; -.
DR STRING; 1943.AQJ64_03885; -.
DR OrthoDB; 3812122at2; -.
DR Proteomes; UP000052982; Unassembled WGS sequence.
DR GO; GO:0018576; F:catechol 1,2-dioxygenase activity; IEA:InterPro.
DR GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR GO; GO:0018506; F:maleylacetate reductase activity; IEA:InterPro.
DR GO; GO:0009712; P:catechol-containing compound metabolic process; IEA:InterPro.
DR CDD; cd08177; MAR; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 2.60.130.10; Aromatic compound dioxygenase; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR InterPro; IPR007535; Catechol_dOase_N.
DR InterPro; IPR000627; Intradiol_dOase_C.
DR InterPro; IPR015889; Intradiol_dOase_core.
DR InterPro; IPR034786; MAR.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00775; Dioxygenase_C; 1.
DR Pfam; PF04444; Dioxygenase_N; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF49482; Aromatic compound dioxygenase; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 10..337
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
FT DOMAIN 379..452
FT /note="Catechol dioxygenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04444"
FT DOMAIN 459..626
FT /note="Intradiol ring-cleavage dioxygenases"
FT /evidence="ECO:0000259|Pfam:PF00775"
SQ SEQUENCE 649 AA; 68326 MW; 360D018CC9A20243 CRC64;
MRSFVHTTGP SRVVFGAGTL SQVSDEVERL GGARVLLLSD GSPALRKDVE RLRAALGDLA
VAEFDGAAMH TPVGVTEQAL GTVREQRVDC LVAIGGGSTT GLAKALAVRT DLPQIIVPTT
YAGSEATPVL GETVDGRKVT RSAPGILPET VVYDIELTLG LPAPISVTSG VNALAHAVEA
LYSPDATPVT DAMALEAVAA IARALPALHD DPSALEARAE LLQAAWLAGT CLGAVGMGLH
HKLCHTLGGT FGLPHADTHT VVLPHAMAYN AAAAPDAMDR VARALGVPDA PTGVFDLIRR
VGGPTSLREL GMAEADLNRA AEAATAQPYP NPREVTRTGL AGLLRDAWQG RRPQPTAGSA
LDLRALTGEV VASFDGCANP RLRQLLSDLA RTLHSYAIRN DLTPREWQRA VDFLTEAGHL
TTDTRQEFIL LSDTLGVSSV VDALANSRTP EATSSAILGP FYVAGPPAAG HGSDIAGGLT
GTPMWADITV TGQEGEPVAD AVVDVWQSNE DGFYDVQLPD LDGPVLRARF TTGADGRFTF
WSILPSEYPI PDDGPVGRML SAVGRHPYRA PHVHFLISAP GHQPLVTQLF VRGGAYLDGA
PGQRDAVFGV KDDLITDFVR HTGPTPDGRP VDGEWRLLEF TFRIARPGH
//
