ID A0A101TC94_9ACTN Unreviewed; 965 AA.
AC A0A101TC94;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=AQJ66_01405 {ECO:0000313|EMBL:KUN89763.1};
OS Streptomyces bungoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=285568 {ECO:0000313|EMBL:KUN89763.1, ECO:0000313|Proteomes:UP000053024};
RN [1] {ECO:0000313|EMBL:KUN89763.1, ECO:0000313|Proteomes:UP000053024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41781 {ECO:0000313|EMBL:KUN89763.1,
RC ECO:0000313|Proteomes:UP000053024};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces bungoensis DSM 41781, type strain
RT for the species Streptomyces bungoensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN89763.1}.
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DR EMBL; LMWX01000003; KUN89763.1; -; Genomic_DNA.
DR RefSeq; WP_061915119.1; NZ_KQ948851.1.
DR AlphaFoldDB; A0A101TC94; -.
DR STRING; 285568.AQJ66_01405; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000053024; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000053024}.
FT DOMAIN 695..954
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 965 AA; 106246 MW; 504FD370147576B1 CRC64;
MTFRTRTRTR TDYVEDVAPG DGALPPRAWY ASSDARSLSL NGSWRLRVSG TADAEDDSFA
AQGYDAGDWA EVPVPGHWVL QGHGSPAYTN HLYPFPVDPP RVPTENPTGD HLRVFDLPAD
WPDLAEGGAV LRFDGVESCA RVWLNGTELG TFKGSRLPHE FAVGHLLKPA GNVLAVRVHQ
WSSGSYLEDQ DQWWLPGIFR DVTLLHRPAG SALDFFVLAA YDHVSGEGTL RVDSDVAGRV
TVPELGIDTA TGEPVTVPVE PWSAEVPRLY DGVLATEGER IPLRVGFRTV ELSDGLIKVN
GRAVLFKGVN RHEWHPRHGR ALDPATMRED VLLMKRHNVN AVRTSHYPPH PAFLDLCDEL
GLWVIDECDL ETHGFTEQAW RDNPVDDDRW TPALLDRAAR MVERDKNHPS VVMWSLGNEA
GTGRGLTAMA EWIRGRDSSR LVHYEGDPDC RDTDVYSRMY AGHAEVERIG RGLDGGNLKR
RRLPFILCEY AHAMGNGPGG LADYQRLFET YDRLQGAFVW EWIDHGIEDQ RFGYAYGGDF
GEELHDGNFV CDGLLFPDRR PSPGLVEYKK VIEPVAVEGD GTGGSVRVTN KYDFADLSAL
AFTWSYEVNG EPVESGALTV PALAPGESAE VKLPEPPVAT AAGEAHWTVR AELAADAPWA
PRGHVVAWGQ FAVSPRRAPS VASTARPVPG DGLITLGPAS FDTRTGALRA VGPVAVDGLR
LDVWRATTDN DDGAAWQTDT RYGPLWRRLG LHRMRHRLDA VEPGEDALTV RTRVAPAACE
IGLSTVYRWT SDGERLRLAV SVRPEGDWTV PLPRLGIRFA LPAADRVQWY GGGPGEAYPD
SRTASLIGRW QSTVDELQTP YVRPQENGAR ADVRWAELGG LRIEGDPEFF LTARRWTTEH
LDAAAHRTDL APGGAVWVNL DHRQHGLGSQ SCGPGPLPRY HLRAEPAAFS FVFSQAGWPS
PASER
//
