ID A0A101TCY8_9ACTN Unreviewed; 1556 AA.
AC A0A101TCY8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Protein kinase {ECO:0000313|EMBL:KUN89974.1};
GN ORFNames=AQJ66_02640 {ECO:0000313|EMBL:KUN89974.1};
OS Streptomyces bungoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=285568 {ECO:0000313|EMBL:KUN89974.1, ECO:0000313|Proteomes:UP000053024};
RN [1] {ECO:0000313|EMBL:KUN89974.1, ECO:0000313|Proteomes:UP000053024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41781 {ECO:0000313|EMBL:KUN89974.1,
RC ECO:0000313|Proteomes:UP000053024};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces bungoensis DSM 41781, type strain
RT for the species Streptomyces bungoensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN89974.1}.
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DR EMBL; LMWX01000003; KUN89974.1; -; Genomic_DNA.
DR RefSeq; WP_061915756.1; NZ_KQ948851.1.
DR STRING; 285568.AQJ66_02640; -.
DR OrthoDB; 3404503at2; -.
DR Proteomes; UP000053024; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011528; NERD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR NCBIfam; NF033442; BREX_PglW; 1.
DR PANTHER; PTHR24347:SF412; CALCIUM_CALMODULIN DEPENDENT PROTEIN KINASE I; 1.
DR PANTHER; PTHR24347; SERINE/THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF08378; NERD; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF47789; C-terminal domain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR PROSITE; PS50965; NERD; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:KUN89974.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000053024};
KW Transferase {ECO:0000313|EMBL:KUN89974.1}.
FT DOMAIN 12..130
FT /note="NERD"
FT /evidence="ECO:0000259|PROSITE:PS50965"
FT DOMAIN 200..497
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 540..828
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 502..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 576
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1556 AA; 170218 MW; 0725F090834980F7 CRC64;
MLEDRWTTVT ESEYEHERRG LEAIRRRLPD EEPWRAWTNF MFTANSGHVR EVDLLVVAPA
GVFLVELKDW HGSVHGGGND WVQTTPSGTS RRHGNPLHLA NRKAKELSGL INGVSGRPAH
RTKIWVGEAV CFTDDKLQVN LPAADMNGVF TVKQLVEMLA VPPGDARYQI TAEASRFVDA
ALKKLRIAPI RRQHEVGSYL LEAKAFDSGP SWADYLGRHS QLHDLARVRV FLSERGASDD
ERRSVERAAA REASVLSRFR HPGAVQLKNY LPSGHPAGPA ILFDYHPETL RLDDYLVQHG
EGLDLQGRLA LVRQLAETVR SAHSRRVHHR TLSAHAVHVI PRDRGPRGRE LGEEQRWLRP
WTQIADWQIA TGQSSSRGRP LTLAPTNVTG FHVAEQADPY LAPELRIPKA DPVRLDVYGL
GVLTYLLVTG QAPGASQSEV MARLEAGESL RPSALVDGLN PDIDDLVEAS TAYEPGRRLS
TVDDFLEMLE YVEQAFVEEV PGGGDAAAGA GGDGGPGENR SEPEKDPLEA VAGDVLAGRW
EVVRRLGTGS TARAFLVRDL EGEPRRSGGL PVAVLKVALS EAKHAVLDRE AEVLGRIHRD
SSIISLYEPQ PLTLAGRRVL VLEYVGDSRE LKDQDGSASK GPRRREDTVA RQLRDNGRLG
MDQLEAYGKY LFGAVEHLEA EGIWHRDLKP DNIAIRVRPN GTRQLVLIDF SLAGYPAKEI
EAGTEGYLDP FVGIITRGSY DGHAERYALA VTLHEMASNE LPRWGDGSVT ARQTDAKEWP
YPQLAADAFE PAVRDGLVAF FRKALARDVK DRFPDLKPME RAWQRIFLDA QQTTAPSTGH
GEKSGRGANG GTDAVAGSAA QPRIGREDDD VSAEQVRDQQ AERADRKTPL SVAGLTVAAQ
SQLFAMGLNT VGDVLDYSAK KFLTAPGMGS RTREEIQRRQ KEWNARLGKA APAPLSAEAR
KAAGQELSDL ERAVAESVTG EVTDPQVLGG LSLDALAARL VPKPSSGSAR SNAKEREAIR
LLLRLPDETG TLPGGLAWVR QRDVADAVGL TAGRIPQIVK KARERWYKDA ALGLLREQLV
ELLAERGRVA PVIELADALI ARRGTQHVER RNRRALALSL LRAVVERESY DNESPPLFRY
FHARMPKGAD PVLGLLALDV REDVDGPDTP ALPALQEYAL NLGVRADRLA ALESLPTAST
VLTELDAVRR PPGSLGWDER RTAEIAVAAS TRAALTPRLE IYPRDLDLVR ALRITQAGVV
AVQPGVEEER QPGLTVDALH KRVATRFPDL GTDPLAPREL PTGSALVRAL KQAGFDLKLA
TRYDKVLRLI PDRPSGDATA GLTSASWGAS AARRSAPTQY DADAAVAAAV KAEQRLMHSA
QQDGFRVLTV PQRRAEDAVR RLAGEPYRAR PVSVTGLFVA ELRGVVGEAA RPTWETVLKA
DAAEPGSRAH QQLRIRTDKA WGRIEPRLRE QLAEADGPLL LTDTAVLARY DALDLIGRLA
EEARQGGSPL WLLVAQSDPA RAPRLAGQSV PYQAGFDEWI VVPDAWVARK HLEPDA
//
