ID   A0A101WZP8_9CREN        Unreviewed;       465 AA.
AC   A0A101WZP8;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Lactate dehydrogenase {ECO:0000313|EMBL:KUO82155.1};
GN   ORFNames=AT714_04985 {ECO:0000313|EMBL:KUO82155.1};
OS   Vulcanisaeta sp. OSP_8.
OC   Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Vulcanisaeta.
OX   NCBI_TaxID=1714252 {ECO:0000313|EMBL:KUO82155.1, ECO:0000313|Proteomes:UP000054992};
RN   [1] {ECO:0000313|EMBL:KUO82155.1, ECO:0000313|Proteomes:UP000054992}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA   Inskeep W.P.;
RT   "The distribution, diversity and function of predominant Thermoproteales in
RT   high-temperature environments of Yellowstone National Park.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO82155.1}.
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DR   EMBL; LOCF01000040; KUO82155.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101WZP8; -.
DR   Proteomes; UP000054992; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR42934; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR   PANTHER; PTHR42934:SF2; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
FT   DOMAIN          36..216
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   465 AA;  50888 MW;  FB24CDC35D6F8127 CRC64;
     MSNRDVIREL EGVFKDRLIT EPHILALYSH DASSEVGMMP MALVYPESTN EITTLVKLAI
     NYGFKLLPVG SSTSLSGNAT PKLGNTVIVA MERMNKIIEV SDVDWVARVQ PGIKVDDLNL
     ELAGYGLQWP VDPASSKTAT VGGVINNGGG GMRGAKFGPA AYWVLGLEVV IGIGDVIRVG
     CRTVKCREGY NLLQLFIGSE GTLGITTEAT LRLAPLPESF VGLMARFRDA ESLVNAVISV
     RRARLWPMVT EFIDDRTAKV LGLEGYYYLW LGVDTYGGSE SQILTKLNDA ISSSNGEVVG
     TASTWQEFSK ILEPRRLLYS ATLKAAFNDY GNDVFVAFED VAVPMGKLPE AVREIQELSA
     KYNIKMILGG HIGDGNLHPS IWARRSDKDE VGRVMRFFED VGRVAIRLGG TISAEHGIGT
     MKKELLRESV SSRNNGNADT VLNLMRNVKK VFDPYGIFNP NKIFD
//