ID A0A101X0L2_9CREN Unreviewed; 369 AA.
AC A0A101X0L2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Peptidase M24 {ECO:0000313|EMBL:KUO82573.1};
GN ORFNames=AT714_01035 {ECO:0000313|EMBL:KUO82573.1};
OS Vulcanisaeta sp. OSP_8.
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=1714252 {ECO:0000313|EMBL:KUO82573.1, ECO:0000313|Proteomes:UP000054992};
RN [1] {ECO:0000313|EMBL:KUO82573.1, ECO:0000313|Proteomes:UP000054992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA Inskeep W.P.;
RT "The distribution, diversity and function of predominant Thermoproteales in
RT high-temperature environments of Yellowstone National Park.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|RuleBase:RU000590}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO82573.1}.
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DR EMBL; LOCF01000027; KUO82573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101X0L2; -.
DR Proteomes; UP000054992; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590}.
FT DOMAIN 7..120
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 153..355
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 369 AA; 40827 MW; 968BACDC9F4AE08D CRC64;
MGLINNRVRR IANLFDELSL DIIVVLDGTN ISYFTGIDSG LMLVIDRSLD TTLIVPRLDF
QRVQDIVGNE ARLIGYSTVE VPQRRSDEVL FVSKGLGDYL LKELGLKPNN IVGIDNTDSP
VAKELGSVGI KTININDRVL GVREVKDEDE VRLIEEASKI TEDSLDKVLK VGLEGRRENE
IAAMLYREMI DGGADDVAFK PIVASGPNGA YPHHVFTNRV IRRGELVTID VGARYHLYCT
DMTRTIAVGQ VSKELRDMAL AVLEAYRKAV NYVKPDVKAS EVDSVARKVL SEYGYSSYYI
HSTGHGVGIE VHEKPVIGPS SSEELRANFV ITIEPGVYIK GVSGVRIEDT ILVTESGPRL
ISKYPVYLF
//
