ID   A0A101XL75_9CREN        Unreviewed;       350 AA.
AC   A0A101XL75;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=3-dehydroquinate synthase {ECO:0000313|EMBL:KUO93460.1};
GN   ORFNames=AT717_01475 {ECO:0000313|EMBL:KUO93460.1};
OS   Vulcanisaeta sp. CIS_19.
OC   Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Vulcanisaeta.
OX   NCBI_TaxID=1714251 {ECO:0000313|EMBL:KUO93460.1, ECO:0000313|Proteomes:UP000054677};
RN   [1] {ECO:0000313|EMBL:KUO93460.1, ECO:0000313|Proteomes:UP000054677}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA   Inskeep W.P.;
RT   "The distribution, diversity and function of predominant Thermoproteales in
RT   high-temperature environments of Yellowstone National Park.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC         Evidence={ECO:0000256|ARBA:ARBA00001941};
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO93460.1}.
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DR   EMBL; LOCG01000105; KUO93460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101XL75; -.
DR   Proteomes; UP000054677; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR   CDD; cd08195; DHQS; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR016037; DHQ_synth_AroB.
DR   InterPro; IPR030963; DHQ_synth_fam.
DR   InterPro; IPR030960; DHQS/DOIS.
DR   NCBIfam; TIGR01357; aroB; 1.
DR   PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR   PANTHER; PTHR43622:SF1; 3-DEHYDROQUINATE SYNTHASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01761; DHQ_synthase; 1.
DR   PIRSF; PIRSF001455; DHQ_synth; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE   4: Predicted;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          54..312
FT                   /note="3-dehydroquinate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01761"
SQ   SEQUENCE   350 AA;  37891 MW;  6B1BF7647180D6CD CRC64;
     MREFTYKSRD GEVRVLINVD YARSLGELIR EYTGCAALVS RGLPDAVKVD CPTMIINDGE
     SGKDINTVLG IIKWVHGLGL DRDGVLIGVG GGSVLDTVGF SASIYLRGVD YINVPTTMLS
     MVDASLGGKT GVNAMGIKNV IGVIRQPRAI IVDLSFLNTL PVHNYVDGFA EVIKYGVTMD
     GELLNYVINN KDALLSKDRG ALEFVVYKSL INKASIVERD ELDKGGERVV LNYGHTVGHA
     VESATEFSVS HGRAVALGMI CEARVGVKLG LTNPDLPKTL LSALDSYGLV TKIDISNIID
     SVTKAISRDK KKSGNFLKLP VVIDVGKWEL VRISVDEFVR MVMSECRSIP
//