ID   A0A101XLA3_9CREN        Unreviewed;       397 AA.
AC   A0A101XLA3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN   ORFNames=AT717_06995 {ECO:0000313|EMBL:KUO93539.1};
OS   Vulcanisaeta sp. CIS_19.
OC   Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Vulcanisaeta.
OX   NCBI_TaxID=1714251 {ECO:0000313|EMBL:KUO93539.1, ECO:0000313|Proteomes:UP000054677};
RN   [1] {ECO:0000313|EMBL:KUO93539.1, ECO:0000313|Proteomes:UP000054677}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA   Inskeep W.P.;
RT   "The distribution, diversity and function of predominant Thermoproteales in
RT   high-temperature environments of Yellowstone National Park.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000256|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family.
CC       {ECO:0000256|ARBA:ARBA00006184, ECO:0000256|HAMAP-Rule:MF_01407}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO93539.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LOCG01000099; KUO93539.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101XLA3; -.
DR   Proteomes; UP000054677; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   CDD; cd18139; HLD_clamp_RarA; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR   PANTHER; PTHR10763:SF26; CELL DIVISION CONTROL PROTEIN 6 HOMOLOG; 1.
DR   PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01407};
KW   Cell cycle {ECO:0000313|EMBL:KUO93539.1};
KW   Cell division {ECO:0000313|EMBL:KUO93539.1};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW   Rule:MF_01407}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01407}.
FT   DOMAIN          44..212
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          302..386
FT                   /note="Cdc6 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01074"
FT   BINDING         56..60
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         200
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         212
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   397 AA;  45422 MW;  2159F610C8EF4755 CRC64;
     MPRIFKNEAA LTPEYIPSKL PYREEQLKEL ETYFSGFLEN PGSMYPKVIL IGRPGSGKTV
     TSRKFGNYVM QSSKVVRYVH VSCFLNRTLI SVLKDVGLQL NIPVPKRGFS TEEMLKILLD
     VVKEKNIYAI ITLDDVFHLV NNSGPHALGT LIRLGEEYVS RGDKYRFGIV LISQDLTFRD
     QLDRSSQSSL GNAIIRFEPY TKDQIFEILL SRAQEALMDG AYDEEILEMI ADVAGVDEWQ
     SNDHRGDARY AIDILWRSAK IAEMRGSDRI LPEHVREAIK NTLRGIRSEE LRMLPLHEKI
     FLLAIVRSLM KNPNSPYIPF GTAENEYQIL CEQYNEEPRK HTQLWEYLKD LNMKGFVETR
     TSSKGMRGRT TLISIPSEPL ATLEEELRKI IGGELGT
//