ID A0A101XT57_9BACL Unreviewed; 595 AA.
AC A0A101XT57;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Oligoendopeptidase F {ECO:0000256|RuleBase:RU368091};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU368091};
GN ORFNames=ATW55_12500 {ECO:0000313|EMBL:KUO97122.1};
OS Ferroacidibacillus organovorans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Ferroacidibacillus.
OX NCBI_TaxID=1765683 {ECO:0000313|EMBL:KUO97122.1, ECO:0000313|Proteomes:UP000053557};
RN [1] {ECO:0000313|EMBL:KUO97122.1, ECO:0000313|Proteomes:UP000053557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITV001 {ECO:0000313|EMBL:KUO97122.1,
RC ECO:0000313|Proteomes:UP000053557};
RA Dall'Agnol H., Nancucheo I., Johnson B., Oliveira R., Leite L., Pylro V.,
RA Nunes G.L., Tzotzos G., Fernandes G.R., Dutra J., Orellana S.C.,
RA Oliveira G.;
RT "Draft genome sequence of Acidibacillus ferrooxidans ITV001, isolated from
RT a chalcopyrite acid mine drainage site in Brazil.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Has oligopeptidase activity and degrades a variety of small
CC bioactive peptides. {ECO:0000256|RuleBase:RU368091}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU368091};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU368091};
CC -!- SIMILARITY: Belongs to the peptidase M3B family.
CC {ECO:0000256|RuleBase:RU368091}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO97122.1}.
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DR EMBL; LPVJ01000006; KUO97122.1; -; Genomic_DNA.
DR RefSeq; WP_067711617.1; NZ_LPVJ01000006.1.
DR AlphaFoldDB; A0A101XT57; -.
DR OrthoDB; 9766487at2; -.
DR Proteomes; UP000053557; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09609; M3B_PepF; 1.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR Gene3D; 1.20.140.70; Oligopeptidase f, N-terminal domain; 1.
DR InterPro; IPR034009; M3B_PepF_4.
DR InterPro; IPR013647; OligopepF_N_dom.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR InterPro; IPR004438; Peptidase_M3B.
DR NCBIfam; TIGR00181; pepF; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11804:SF45; SIMILAR TO OLIGOENDOPEPTIDASE; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR Pfam; PF08439; Peptidase_M3_N; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU368091};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU368091};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU368091};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU368091};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU368091}.
FT DOMAIN 113..182
FT /note="Oligopeptidase F N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08439"
FT DOMAIN 203..577
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 595 AA; 66927 MW; D5BE55D8AB79EC20 CRC64;
MHRAKRSDVP LQETWDLTDL FESHTAWEAE LDAIRTALPS VTKYQGRLAE GAEVLAACLE
AREALQIRMN RVASYATFRL STDSLDPNHQ ADTVRVATLD TECSTKTAFI QSEVLALPDG
TVESWMAGDA ALHAFRPTLH NWLEIRPYRL SAEVESALLG LSQTLSAPQR IYTLSKGADM
RFDQALDKDG QAHPVHDGGS QLSPDPILRR NAYASFTRGL RAYRTTYAAT FAAEVEKNVT
LAKMRGYDSA TQMLLHPHKV DESVYHSIHD VIRTELAPHM RRYQRLRQRL LGLDKMLYCD
LTVQLPDGPT VTYEQGRMWI LDALQVLGEE YHEIIRRAFA KRWIDRSDNL GKRSGAFCNT
VYGVHSYVFM TWENHTRAVF TLAHELGHAG HLSLAAKYQK QSNSRPPMSF IESPSTMNEL
LLAQHLLKQS DDKRMRRSVI AGLMGTYHHN FVNHLLEGEL QRRIYRAAEA GTPITEQMLT
RVKGEILAEF WGDTVEIDEG AALTWMRQPH YYMGLYPYTY ALGLSISTAA AQAIESQGEP
AIKRWIDVLK AGGTKTPAEL AWMAGADITN PDVIRSAVAY VGTLVDAFEA TLDEF
//
