ID A0A103E1P1_9BURK Unreviewed; 446 AA.
AC A0A103E1P1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=WS67_14000 {ECO:0000313|EMBL:KVE26715.1};
OS Burkholderia singularis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=1503053 {ECO:0000313|EMBL:KVE26715.1, ECO:0000313|Proteomes:UP000062788};
RN [1] {ECO:0000313|EMBL:KVE26715.1, ECO:0000313|Proteomes:UP000062788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSV85 {ECO:0000313|EMBL:KVE26715.1,
RC ECO:0000313|Proteomes:UP000062788};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVE26715.1}.
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DR EMBL; LOWA01000032; KVE26715.1; -; Genomic_DNA.
DR RefSeq; WP_059517256.1; NZ_LOWA01000032.1.
DR AlphaFoldDB; A0A103E1P1; -.
DR OrthoDB; 9785252at2; -.
DR Proteomes; UP000062788; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR PANTHER; PTHR44936:SF13; HISTIDINE KINASE; 1.
DR PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KVE26715.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000062788};
KW Transferase {ECO:0000313|EMBL:KVE26715.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..435
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 406..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 241..268
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 446 AA; 47885 MW; 77AFB0D6A4D398B7 CRC64;
MQRRITTTTA SGRVNLSHLF WLRNLAIIGQ LVTIAVVQAY FGVHLPLPAM LMVIALEIVF
NALTWVRVLR ARPETNFELL GQLWVDLGAL SALLFLSGGT TNPFVSLYLP SLAIAAAVLP
WHLMIWLAAF AVACYLALGF DSVPLNLDNP ANLFDYFRAG MWVNFMVSVG LIAWFVARMS
SALRQRDAAL GEAQQALLHD ERAVALGVQA ATVAHEMGTP LSTIAMLTEE LREAARTDSG
LARYDADLKV LEEQMSQCTS ALARLRSRAS ERPNRQSVAA WLGTFVEHWR LRHPHVRFEQ
LGPQPRGVVL DDTVAVGQIL TILLDNAARA SRDRVTLAAA TVHDGARDEI VFEVCDNGAG
IPAALRDALG SMPVDSTQGG HGVGLYLAFS AAARLGGSIE LADAKPRAAG ATPGRSAEAA
SGRGTRAILR VPVERESGGS LGTDAA
//
