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Database: UniProt
Entry: A0A109BLD6_HYPSL
LinkDB: A0A109BLD6_HYPSL
Original site: A0A109BLD6_HYPSL 
ID   A0A109BLD6_HYPSL        Unreviewed;       528 AA.
AC   A0A109BLD6;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   05-JUL-2017, entry version 11.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=APY04_0588 {ECO:0000313|EMBL:KWT70926.1};
OS   Hyphomicrobium sulfonivorans.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Hyphomicrobiaceae; Hyphomicrobium.
OX   NCBI_TaxID=121290 {ECO:0000313|EMBL:KWT70926.1, ECO:0000313|Proteomes:UP000059074};
RN   [1] {ECO:0000313|EMBL:KWT70926.1, ECO:0000313|Proteomes:UP000059074}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WDL6 {ECO:0000313|EMBL:KWT70926.1,
RC   ECO:0000313|Proteomes:UP000059074};
RA   Albers P.;
RT   "Transcriptomic analysis of a linuron degrading triple-species
RT   bacterial consortium.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KWT70926.1}.
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DR   EMBL; LMTR01000027; KWT70926.1; -; Genomic_DNA.
DR   EnsemblBacteria; KWT70926; KWT70926; APY04_0588.
DR   PATRIC; fig|121290.4.peg.1058; -.
DR   Proteomes; UP000059074; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000059074};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059074}.
FT   DOMAIN      220    351       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      436    505       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     228    235       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   528 AA;  58884 MW;  0BE8D1706C9BAA91 CRC64;
     MHTIHKADHS VTGSYAGAAQ GGMEERAVAE PISAGSLTST TTTALATTGS DEPRGQKVRA
     MLRARLGDDI YTSWFNALEF ESFDGGTVRF SVPVKFLRTW IQSHYSEDLL DCCRAEFKGA
     EKVEVALRQP GNQAAARVEA APAPSEQAAA LRNNAQPDAA QRNTTFVAPA PAGRTSVGGF
     EGSPLDPRYT FESFVVGPSN RMAHAGATQV AETALGGVPG FNPLYLHSAV GLGKTHLLHA
     IAWEVKRRSP NAQVLYLTAE RFRYQFVEAL RSQDPLAFKE KFRDINVLLI DDLEFMHGER
     TEQEFDHIIN SLLDGGRQVV VASARAPNHV ERLNERMRSR LQRGLVTEIA TLDYELRLKV
     LETRLAEKRA LDPSFTLGRE IISLLAERLT ESGRELEGAI TRLYATWQYM RTAITPDVAE
     TVIRDLVQGL EPRRIKIEDI LRIVSRHFGV SKGDLLSQRR HRSVVWPRQI GMYLAKQLTA
     RSLPEIGRRF GNRDHTTVLH AIRKIEGELS GNPRLKEELE ELKRLLSH
//
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