ID A0A109FE42_9BASI Unreviewed; 434 AA.
AC A0A109FE42;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=NAD(P)-binding protein {ECO:0000313|EMBL:KWU42776.1};
GN ORFNames=RHOSPDRAFT_35726 {ECO:0000313|EMBL:KWU42776.1};
OS Rhodotorula sp. JG-1b.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1305733 {ECO:0000313|EMBL:KWU42776.1, ECO:0000313|Proteomes:UP000062823};
RN [1] {ECO:0000313|EMBL:KWU42776.1, ECO:0000313|Proteomes:UP000062823}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JG-1b {ECO:0000313|EMBL:KWU42776.1,
RC ECO:0000313|Proteomes:UP000062823};
RG DOE Joint Genome Institute;
RA Goordial J., Raymond-Bouchard I., Riley R., Ronholm J., Shapiro N.,
RA Woyke T., Grigoriev I.V., Labutti K.M., Greer C., Whyte L., Bakermans C.;
RT "Draft genome of eurypsychrophile Rhodotorula sp. JG1b isolated from
RT permafrost in the hyper-arid Upper Elevation McMurdo Dry Valleys,
RT Antarctica.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
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DR EMBL; KQ954501; KWU42776.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A109FE42; -.
DR STRING; 1305733.A0A109FE42; -.
DR OrthoDB; 1133at2759; -.
DR Proteomes; UP000062823; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000062823}.
FT DOMAIN 16..232
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 434 AA; 48072 MW; C04865ED11DE5474 CRC64;
MTSPRLRRAF APESYAVIGG EGFLGAALVS ELLERHPASS VASFGLTQRR FDTPTGGDPY
RFFRTDITSY DSILSALRDS AATTVFHTAS PHAKSTPEVW RKVNIEGTDA VVRACREAGV
RKLVFTSSMT VVYEPGTPYK NVDERLPIIE TEEKVATYAG SKAAAEKIVL AANGQDGLKT
PGDRQVLPGF IKVYKSGQSV FQMGDNSNLF DFVTVKNVVH AHLLAAERLD APPLPASTFV
TRLEPVQCTV KRRPLPTSRY QHVIDPSKPA PPPDPPLPAV RNKWNQFACS DDKPVSAENL
TVAGQAFFIT NGEPVNFWTF ARAVYFEYSQ RPPRWWDPLV FPKEVGMLYA SLSETIGWFQ
GKKPEDCAVP KAYMQQVLHD LYCDIERARR LLGYEPIESL EEGIRTGVAW YKADEARQER
QAAAGAGDSL PKRS
//
