ID   A0A109II46_9ACTN        Unreviewed;       350 AA.
AC   A0A109II46;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:SCG50423.1};
GN   ORFNames=GA0070623_1811 {ECO:0000313|EMBL:SCG50423.1};
OS   Micromonospora rifamycinica.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=291594 {ECO:0000313|EMBL:SCG50423.1, ECO:0000313|Proteomes:UP000198226};
RN   [1] {ECO:0000313|EMBL:SCG50423.1, ECO:0000313|Proteomes:UP000198226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44983 {ECO:0000313|EMBL:SCG50423.1,
RC   ECO:0000313|Proteomes:UP000198226};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT607752; SCG50423.1; -; Genomic_DNA.
DR   RefSeq; WP_067311893.1; NZ_LT607752.1.
DR   AlphaFoldDB; A0A109II46; -.
DR   OrthoDB; 9814210at2; -.
DR   Proteomes; UP000198226; Chromosome i.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR020030; Pseudaminic_synth_PseI.
DR   InterPro; IPR013974; SAF.
DR   NCBIfam; TIGR03586; PseI; 1.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF2; PSEUDAMINIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
SQ   SEQUENCE   350 AA;  36723 MW;  5D531E7B08EF720B CRC64;
     MTTTVKIGPH VVGAGEQPFV VAEMSGNHNG DLGRALAIVD AVAASGAHAL KLQTYRPDTI
     TIDVDTPAFR ISGGHELWGG QNLYRLYERA HTPYEWHEPI FTRARERGLT VFSSPFDPSA
     VELLEGLDVP AYKIASSELV DLPLIRLVAG TGKPLVISTG MATVAEIDAA VRTARDGGAG
     GIVLLACTAS YPAPPADSNL RRIPVLADAF GVPVGLSDHT PGIGVPVASV ALGACFIEKH
     VTLDRTDGGV DSDFSLNPDE LAALVVESAR AHAALGGTAI GPTPAEREGL RFRRSLFVVA
     DVRAGDKVTA ANVRSIRPAG GLPPVEIDRV LGRTFTTDVP RGTPLTWDLV
//