ID A0A117E1R3_ASPNG Unreviewed; 729 AA.
AC A0A117E1R3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit {ECO:0000256|ARBA:ARBA00015765};
DE AltName: Full=ERF-3 {ECO:0000256|ARBA:ARBA00031881};
DE AltName: Full=ERF2 {ECO:0000256|ARBA:ARBA00030845};
DE AltName: Full=Polypeptide release factor 3 {ECO:0000256|ARBA:ARBA00029585};
DE AltName: Full=Translation release factor 3 {ECO:0000256|ARBA:ARBA00030210};
GN ORFNames=ABL_04968 {ECO:0000313|EMBL:GAQ42307.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ42307.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ42307.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BCMY01000007; GAQ42307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A117E1R3; -.
DR PaxDb; 5061-CADANGAP00008625; -.
DR VEuPathDB; FungiDB:An11g04510; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1138990; -.
DR VEuPathDB; FungiDB:ATCC64974_90520; -.
DR VEuPathDB; FungiDB:M747DRAFT_369683; -.
DR OMA; ARFDECT; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03704; eRF3_C_III; 1.
DR CDD; cd04089; eRF3_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003285; Sup35.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF36; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01343; YEASTERF.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 282..515
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 78094 MW; 036BE7F9790D5E93 CRC64;
MADQTPDSWE DELSRQTEGV RLNPNAQGRP QPQAPSFHPG AATFTPGAAS FVPGQTYQPY
GGGYPQYGQY GQQAYGGYPY DQQQQAYAQY GAYAQQPGGF NNNQVYNQQY GGYQQQQQQP
RQAAAAPAAA QPAQPAPKPA ASNNAAPPKA KVLSIGGASN SPAAPKTKVL SIGTPSPAPT
SSTPSSTSGA ATPGDTKGAA AVEAAAKVTA SKAIEKTEKK ADAKAAASGK SSPTPSGRSS
PGRSSPARGE AAKAARNADA VAMEQQADVD EATLKEIYGE KKEHVNIVFI GHVDAGKSTL
GGSILYVTGM VDERTLEKYK RDAKEAGRET WYLSWALDLT NEERAKGKTV EVGRAHFQLP
VKAADGSTIT RHFSILDAPG HKSYVHHMIG GASQADVGVL VISARKGEYE TGFEKGGQTR
EHALLARNTG VKTLIVAVNK MDDPTVEWSK ARFDECTVKV GKFLENLGYK KSDLFFMPIS
AQRTTGIKDR VPTDLAPWYG GPSLLEFLSD MKVPERKINA PFMMPISAKY RDMGTMVEGR
IESGVLKKNG SCIMMPNRTK VEIAALYGET EDEIPTGTCG DQVRLRLRGV EEEDILPGFV
LCSPKRLVNC VKTFEAKIRI LDLKSILTAG YNCVMHVHSA VEEVTVAALL HKCEPGTGRR
SKRPPPFAAK GQTIIARIEV TSTAGAVCVE RFEDYNQMGR FTLRDQGQTV AIGMITKLIS
AEEAAATQA
//
