ID   A0A117M538_9FIRM        Unreviewed;       726 AA.
AC   A0A117M538;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:KUK84822.1};
GN   ORFNames=XE00_0513 {ECO:0000313|EMBL:KUK84822.1};
OS   Desulfofundulus kuznetsovii.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC   Desulfofundulus.
OX   NCBI_TaxID=58135 {ECO:0000313|EMBL:KUK84822.1, ECO:0000313|Proteomes:UP000054111};
RN   [1] {ECO:0000313|Proteomes:UP000054111}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA   Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA   Andersen G.L., Banfield J.F.;
RT   "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT   Other Microbial Community Members in Biogeochemical Transformations in Oil
RT   Reservoirs.";
RL   MBio 7:e01669-15(2015).
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUK84822.1}.
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DR   EMBL; LGGU01000012; KUK84822.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A117M538; -.
DR   PATRIC; fig|58135.3.peg.2; -.
DR   Proteomes; UP000054111; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR   CDD; cd06577; PASTA_pknB; 1.
DR   Gene3D; 3.30.10.20; -; 2.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 2.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000313|EMBL:KUK84822.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          600..660
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
FT   DOMAIN          666..725
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   726 AA;  78347 MW;  F35620AA12150CAD CRC64;
     MPDLDPAKKS FTTKRVALVF ILISLALFGL VSRLFWVQAV WGPGLKRQAE EYHTQDVTVQ
     PERGSIYDRN HNELVTNIPA FSVYAQSKKI KDPAGLSEKI APVLGIKQAL VYEKLCSKEP
     FIWLTHNLEY SAAERLKNLS KELGGNPDKD SKKDPDLQWI GLIESNKRSY PQGSMAAHLL
     GFVGSDNQGL TGLENSYDSY LKGKPGSSTI ESDAKGLPVP QAQTDVNPSD PGANLVLTID
     QTIQFFVERE LDNLVASYKP ARAAIIVMDP ATGQILAMGN RPAFNPGNWS KEPESVWGGD
     TAVLYNYEPG STLKMFIAAA ALEKRFVSPG ERLYDPGSIV VKGRRIYCAE REGHGSLTFS
     EAVSVSCNVA LIQVGQRLGK ENIYKYLQEF GFGARTGIDL PGEESGVLMD KKKATELDLA
     TMSIGQSIAV TPIQLITGAC AIANGGKLMK PYLVKALEDD QRKIVKEFKP QEVRSIISSE
     TARTLTSMME DVILEGTGTK AQVEGYRIAG KTGTAQIPGP KGYIEGKYVA SFLGYGPLDN
     PRAAVLVIVD EPKGSKYHGG EVAAPAFQSV MRDTLVYLGI PQEKTGAQKS EEELPDPSKV
     PSRVAVPNVI GFPAEQATRL IKNRGLVCWA SAPQGVISGQ KPGGGSNLIK GSLVTLKVTP
     FDLSKPPDKI TVPDLKSLTL KKAAVLLEEI GLKLKAEGSG LALYQSPPAG TGVKPGSVVK
     VYFNPE
//