ID A0A117RCD2_9ACTN Unreviewed; 314 AA.
AC A0A117RCD2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:KUN83086.1};
GN ORFNames=AQJ66_19490 {ECO:0000313|EMBL:KUN83086.1};
OS Streptomyces bungoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=285568 {ECO:0000313|EMBL:KUN83086.1, ECO:0000313|Proteomes:UP000053024};
RN [1] {ECO:0000313|EMBL:KUN83086.1, ECO:0000313|Proteomes:UP000053024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41781 {ECO:0000313|EMBL:KUN83086.1,
RC ECO:0000313|Proteomes:UP000053024};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces bungoensis DSM 41781, type strain
RT for the species Streptomyces bungoensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN83086.1}.
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DR EMBL; LMWX01000031; KUN83086.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A117RCD2; -.
DR STRING; 285568.AQJ66_19490; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000053024; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KUN83086.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053024}.
FT DOMAIN 19..287
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 314 AA; 33361 MW; 5220FFEC7DAFFD63 CRC64;
MTADALPMVV PDSGLPARVR IHEVGARDGL QNEQRAVPTP VKAEFVRRLA EAGLTTIEAT
SFVHPKWVPQ LADAEQLFPQ LAGLGNIDLP VLVPNQRGLE RALALGARRI AVFASATESF
AKANLNRGLD ESLAVFEPVV RQAKDAGVHV RGYVSMCFGD PWEGAVPLRQ VARVCTALRD
MGCDELSLGD TIGVATPGHV RELLALLNEE GVPTHEIGVH FHDTYGQALA NTLAALQHGV
TTVDASAGGL GGCPYAKSAT GNLATEDLVW MLHGLGIETG VDLGRLTATS VWMAEQLGRP
SPSRTVRALS HKDQ
//
