ID   A0A117S149_9ACTN        Unreviewed;      1051 AA.
AC   A0A117S149;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=LuxR family transcriptional regulator {ECO:0000313|EMBL:KUO20630.1};
GN   ORFNames=AQJ91_13820 {ECO:0000313|EMBL:KUO20630.1};
OS   Streptomyces dysideae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO20630.1, ECO:0000313|Proteomes:UP000053260};
RN   [1] {ECO:0000313|EMBL:KUO20630.1, ECO:0000313|Proteomes:UP000053260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RV15 {ECO:0000313|EMBL:KUO20630.1,
RC   ECO:0000313|Proteomes:UP000053260};
RA   Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA   Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT   sponge.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO20630.1}.
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DR   EMBL; LMXB01000032; KUO20630.1; -; Genomic_DNA.
DR   RefSeq; WP_067020519.1; NZ_KQ949081.1.
DR   AlphaFoldDB; A0A117S149; -.
DR   STRING; 909626.AQJ91_13820; -.
DR   OrthoDB; 499349at2; -.
DR   Proteomes; UP000053260; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR   PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053260};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          15..85
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|SMART:SM00862"
FT   DOMAIN          92..240
FT                   /note="Bacterial transcriptional activator"
FT                   /evidence="ECO:0000259|SMART:SM01043"
SQ   SEQUENCE   1051 AA;  111719 MW;  D7AAC3A1B4F4DFA4 CRC64;
     MTTDLTLLPR VAYRGQEVTA PRLRGLLALL AGDLRTGCST ERLVQGLWPD ELPERPAKAV
     QVLVSRARAQ LGADVLASTP TGYRLALAED QVDSSALLLR AAASADRARA GDHAGSLAAA
     EAGLALWEGT SDGAGGPDET ADPVAALRAE RAPVRGTLVR AQALALARLG RHAEAAGPLA
     VAAAEHPRDE EVLAELLRGE AASAGPSAAL MRYEAYRREL RDELGTDPGA GLKAVQRELL
     RGEAPVVRHG VPHEPNPLLG RDEDIAAVER LLRASRAVTV VGPGGLGKTR LAHAVSRRAE
     QRVVYFVPLA GVTADEDVTA EVASALGAGE GRAGAMSGHA PADPVSGILG ALGSGPALLV
     LDNCEQVIRG AAGLVQALVS SSKDLRVLAT SRAPLGLTSE AVYALPELGL GTSVELFTQR
     ARAARPGVEL PPDAVAELCR HLDGLPLAVE LAAARVRVLS VPDIARRLGD RFALLRGGAR
     DVPERHRTLH AVVDWSWNLL DEEARAALRT LSVFPGGFSG EAAEHVLGED ALFLLEQLAD
     QSLLTVADTP AGVRFRMLET VREFSAARRA EAGEEEEAVG RFLAWARDFG VTYHDWLLGS
     QPGTAWERIR AEQDNLVLAL RHALVRTDGP TTAALTAVLA ALWSTGSNYP RLTALAADTG
     PPLSHYYPEP EYVEVARAAA VFCTASLFMG YGPRAVRHLV TLRRLPPAPL DTLLRAIAAV
     LSAVPEMLPP DYDVLRGLCA SEQPLLAGVA EGVATYVWEY EHDLDRALAS ARRIIAALAP
     VDTPFLQVMG HARLSELYMQ TEQGNAAYGH LKAALEALPR LGDEHDTIGV RWGLVLACLH
     RGDPDEAEYW LRQAEGDNAP QKYDFYSPDF GGRAEIALAR GLTEVGLGLW RNAVERMPAA
     GSLDGDDPFF DRWSLQVQSA AVTAHAHAGR LELVAGQVDR LRQELRRLLS GPSRSPMELP
     LFGTVLHALG MAGLASGDAT AVRMIALAER LRVLREFQPT MSADRARQAA GAAGKAARAA
     YADAVSEYAA LERDELREAA RAVMAVTSGR G
//