ID A0A117SEP2_9FLAO Unreviewed; 684 AA.
AC A0A117SEP2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=APF83_13900 {ECO:0000313|EMBL:KUO67205.1};
OS Lutibacter sp. BRH_c52.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Lutibacter.
OX NCBI_TaxID=1734397 {ECO:0000313|EMBL:KUO67205.1, ECO:0000313|Proteomes:UP000054346};
RN [1] {ECO:0000313|EMBL:KUO67205.1, ECO:0000313|Proteomes:UP000054346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRH_c52 {ECO:0000313|EMBL:KUO67205.1};
RA Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT "Microbial metabolic network in the subsurface.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO67205.1}.
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DR EMBL; LOEY01000045; KUO67205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A117SEP2; -.
DR Proteomes; UP000054346; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43711:SF32; DRUG SENSORY PROTEIN A; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13424; TPR_12; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50005; TPR; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 399..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 81..114
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 121..154
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 161..194
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 241..274
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 465..683
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 684 AA; 78062 MW; 1A438AD94BF689C9 CRC64;
MKNRLIILFY LGFSSLIIGQ EAADINKLKK ELQQELVDTA KVTLHLKIAN LYLKTKPDSS
LVNLTKALEL AKKSAYQPKI AQVYNRIGRY YEKIVDYKDA IKNYNDAFLI FEKLGDKKKM
AEIYNSLGTN YSELYAEDRA IEYYLKSLAF HKEVQDQKGI ASNYTNIGNL YYNEENYDLA
EKYFRDALLI YEKLDDKYGI SSSYTNIANA LADNGRVEEG LNYYKKSIAI EDKLGDQYGI
AINYNNIGDC YINLKQYIQA MEYLDKAMKI ADSLGEKDLQ SIVLLNIADV ENKQKRFQRA
IYAARESYAI ADLIGNLDYK TENLLQASIA YEGLGDNALA LKRLKEYTTI KDSLLKMDRL
KKIKLFNTLN ELEKSQYTIE DLSKTSEEAQ LNYEKEKKYT HFLIIAIVVF AFLLILLIQQ
NASKKKAFNL LEYKNYQVHK MKDEIDGQSN KLKQLNSTKD KFFSIIAHDL KNPFNSIAGF
TELMIENNEI YDKEKRLKFL KIIKGSSAKV SSLLDNLLIW ASSQSGNLKF NPKNINLALQ
VTGVISFLEI QAINKDIAIL NRVEKNVYVK ADENMLDTIL RNLISNAIKF TQPKGEIHIY
SVLKKDFVEI TVKDNGVGMS ADEIAAIFSV NEINSSLGTF NEQGSGLGLI LCSDFVESHG
GKIWVESVVN QGSEFKFTLP IWKD
//
