ID A0A120JWC5_9GAMM Unreviewed; 629 AA.
AC A0A120JWC5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=LOKO_02601 {ECO:0000313|EMBL:AMD01661.1};
OS Halomonas chromatireducens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=507626 {ECO:0000313|EMBL:AMD01661.1, ECO:0000313|Proteomes:UP000063387};
RN [1] {ECO:0000313|EMBL:AMD01661.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD01661.1,
RC ECO:0000313|Proteomes:UP000063387};
RX PubMed=26988058;
RA Sharko F.S., Shapovalova A.A., Tsygankova S.V., Komova A.V.,
RA Boulygina E.S., Teslyuk A.B., Gotovtsev P.M., Namsaraev Z.B.,
RA Khijniak T.V., Nedoluzhko A.V., Vasilov R.G.;
RT "Draft Genome Sequence of 'Halomonas chromatireducens' Strain AGD 8-3, a
RT Haloalkaliphilic Chromate- and Selenite-Reducing Gammaproteobacterium.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|EMBL:AMD01661.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD01661.1,
RC ECO:0000313|Proteomes:UP000063387};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014226; AMD01661.1; -; Genomic_DNA.
DR RefSeq; WP_066449885.1; NZ_CP014226.1.
DR AlphaFoldDB; A0A120JWC5; -.
DR STRING; 507626.LOKO_02601; -.
DR KEGG; hco:LOKO_02601; -.
DR PATRIC; fig|507626.3.peg.2604; -.
DR OrthoDB; 798937at2; -.
DR Proteomes; UP000063387; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000063387};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..629
FT /note="VWFA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007167058"
FT TRANSMEM 586..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..220
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 629 AA; 69369 MW; 29120E019C580C5B CRC64;
MGRVLHKSWL WLAVLLGPAL LSGSLPAAPL EERPDVRVII DVSGSMRHND PEQLAAEALE
LLVALLPSGA RAGVWTFGER VENPLPLGPV TSAWREQAMS LSPRLVEYQQ FTDIESAIRE
AAAPETDGHR HLVLLTDGVI DLSPRLGAKP GIDDVSRRTL LESLGPRLTA GDVAIHAIAF
SDEADLDLVE RLSQQTGGLS APVESPDALL GAFLNIFDRI FPSDRLPLTD DQFLVEPGLD
GFTALLFRKA PDEAEGRERS PAVLIAPDGR RFTVEAPPDG ATWRSESRYD LIQVPDPMPG
QWRLEGGVNK DSRITIVSPL SLQTGGIPGT LYLGFDVPLE AWLTHDGEVL GQDALPAHLE
MTAILHDDKG STQSAVVLEQ AADRFTGTLP APALTGTAQL VIRAEGQGFR RQRIQAVNVL
PAIAARHEAE SDRVLLTAEH PLLNHDNTRL HGQLQGARLD AEPQAARRWL IGLPELDPGL
SQPLLLRAEV TLDGETRELR LPRLVLFPHS ETAIDQAAGP TVLSIERFHE ELDLLPESSS
PTSQSGGMDR FLSLVERLPL LAQSQWDDWR PILDRQLEAG RQDPRVWGLV LLVVVVLLLL
GLTWRRQQRR QQRRRRRRFT TTRREEPHV
//
