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Database: UniProt
Entry: A0A124EGX9_9ACTN
LinkDB: A0A124EGX9_9ACTN
Original site: A0A124EGX9_9ACTN 
ID   A0A124EGX9_9ACTN        Unreviewed;       520 AA.
AC   A0A124EGX9;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   05-JUL-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   ORFNames=AUL39_00620 {ECO:0000313|EMBL:KUH58887.1};
OS   Olsenella scatoligenes.
OC   Bacteria; Actinobacteria; Coriobacteriia; Coriobacteriales;
OC   Atopobiaceae; Olsenella.
OX   NCBI_TaxID=1299998 {ECO:0000313|EMBL:KUH58887.1, ECO:0000313|Proteomes:UP000054078};
RN   [1] {ECO:0000313|EMBL:KUH58887.1, ECO:0000313|Proteomes:UP000054078}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK9K4 {ECO:0000313|EMBL:KUH58887.1,
RC   ECO:0000313|Proteomes:UP000054078};
RA   Li X., Borg B., Canibe N.;
RT   "Draft Genome Sequence of Olsenella scatoligenes SK9K4T; a Producer of
RT   3-Methylindole- (skatole) and 4-Methylphenol- (p-cresol) Isolated from
RT   Pig Feces.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUH58887.1}.
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DR   EMBL; LOJF01000001; KUH58887.1; -; Genomic_DNA.
DR   RefSeq; WP_059052613.1; NZ_LOJF01000001.1.
DR   EnsemblBacteria; KUH58887; KUH58887; AUL39_00620.
DR   Proteomes; UP000054078; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054078};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054078}.
FT   DOMAIN      193    335       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      426    495       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   520 AA;  58353 MW;  51632927E2CD8D98 CRC64;
     MEPEIDSDTE ALWQDMFDLV SKRHLPGSVM AMLRSCAPTS LDAGVLHVET HSRTVKNRLS
     KNLDVINECL TEAAFEPTTL DISFVQDPDA APLAPNSAVT PEEARRWMAP SPQTAAPTPA
     PAPAPLQRNP EDAWLDENAA REAAGHERRA ANPLVDDISE MDSKLTFDRF VVGDENTFAY
     QAALQVANGE NRTYNPLFIY GKSGLGKTHL LRAIQNYISA NDPTRVCVYK DGSSFITDYT
     TAMSHRERSA PDILRDHYYD IDVLIIDDIQ KLAGKAGTID FFFDAFNHLT SAGKQIVLAA
     DRSPSQLGAE AAFDERVTSR LDSGFSTSIQ VPNYELKLRL ITTFCERMHE DAAEGHVGLA
     ITGTISEDNI RYMAERAGTN IRVIEGFCQR CLIAETHREQ RGEELSHEDI NRLAKESWPN
     GEKQYKIEEI QRAVEQYFDI SHSDLVGEKR NKDIMNARHI AVWLSKELCD ATYAEIGEHF
     GGRSHATMLN SIRVVDKKRK EDKIYHDRLV QIRDNITENT
//
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