ID A0A124FT57_9FIRM Unreviewed; 934 AA.
AC A0A124FT57;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA methylase N-4/N-6 domain protein {ECO:0000313|EMBL:KUK64362.1};
GN ORFNames=XD84_1495 {ECO:0000313|EMBL:KUK64362.1};
OS Desulfotomaculum sp. 46_80.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Desulfotomaculum.
OX NCBI_TaxID=1641375 {ECO:0000313|EMBL:KUK64362.1, ECO:0000313|Proteomes:UP000053828};
RN [1] {ECO:0000313|Proteomes:UP000053828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK64362.1}.
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DR EMBL; LGGF01000030; KUK64362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A124FT57; -.
DR PATRIC; fig|1641375.3.peg.1344; -.
DR Proteomes; UP000053828; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KUK64362.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 156..485
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 934 AA; 106395 MW; 9A359E29D4DA7DAB CRC64;
MSGNTTKKTI ETITHDEASR KNIPTAEYQS IMAKDEQNPV RVAYERRNRD LDPQLIWRGK
DEQDWSDLVV HAPPLYIQEK IHPKALIDDL IRRTKVQEKA EDQQLNLFAD FNGLPDENAR
TEFYQHDANW TNRMILGDSL QVMASLAERE GLRGKVQCIY IDPPYGIKFN SNFQWSTTSR
DVKDGNVDHI TREPEQVKAF RDTWRDGIHS YLTYLRDRLT LARDLLTESG SIFVQIGDEN
VHRVRALMDE VFGESNFVSE ILLKKGGTAT SNYLPTTSDF ILFYAKKIET LKYRQLFFSK
EIGIGESTGQ RYDQLELQNG KRRALSIDEK KNPNLIPSDG RPFKYSNPCS MHENHYHRVN
PLIVNGCPFT PPSDRQWSSH PDLMKRVVLS NRIVSTGKNL AYVMYIDDYP VVPVNNFWTD
ALLRSAKQYI VETAPLVIAR CILMTTDPGD LVLDPTCGSG TTAYVAEQWG RRWITIDTSR
VALTLARARL MGARYPYYLL ADSRDGQIKE AEVTRTVPSI APTRGDIRQG FVYELVPHIT
LKSIANNAEI DVIWEKYQEI LEPLREKLNK ALSENWEEWE IPRDADKKWP NETKEIHSQW
WKHRITRQKE IDSSIAAKAE FEYLYDKPYE DKKKVRVAGP FTVESLSPHR VLGVDENDEL
IDKLAESTEG YGEERGFVRM ILENLKTSGV QQAHKEDKIN FASIKPWPGD LICAEGRYTE
GDEESAAEKR AAIFIGPEFG TVSRPDLVAA AREAGDADFD VLITCAFNYD AHSSEFAKLG
RIPVLKARMN ADLHMADDLK NTGKGNLFVI FGEPDIDILD AGNGQIQVKI NGVDVFHPNT
GEVRSDGAEG IACWFIDTDY NEESFFVHHA YFLGANDPYK ALKTTLKAEI NAEAWEALHS
DTSRPFDKPT RGRIAVKVIN HLGDEVMKVF RVKG
//
