ID   A0A124HG76_9ACTN        Unreviewed;       837 AA.
AC   A0A124HG76;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:KUN06147.1};
GN   ORFNames=AQI95_14695 {ECO:0000313|EMBL:KUN06147.1};
OS   Streptomyces yokosukanensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67386 {ECO:0000313|EMBL:KUN06147.1, ECO:0000313|Proteomes:UP000053127};
RN   [1] {ECO:0000313|EMBL:KUN06147.1, ECO:0000313|Proteomes:UP000053127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40224 {ECO:0000313|EMBL:KUN06147.1,
RC   ECO:0000313|Proteomes:UP000053127};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces yokosukanensis DSM 40224, type
RT   strain for the species Streptomyces yokosukanensis.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|ARBA:ARBA00008708}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUN06147.1}.
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DR   EMBL; LMWN01000018; KUN06147.1; -; Genomic_DNA.
DR   RefSeq; WP_067122571.1; NZ_KQ948210.1.
DR   AlphaFoldDB; A0A124HG76; -.
DR   STRING; 67386.AQI95_14695; -.
DR   Proteomes; UP000053127; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR021904; DUF3516.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF12029; DUF3516; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KUN06147.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053127}.
FT   DOMAIN          39..195
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          215..419
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   837 AA;  93663 MW;  DB96FFA975DB69E7 CRC64;
     MTLIDQLPPT ADPDALYEAF ESWALERGLT LYAHQEEALI EAVSGANVIV STPTGSGKSM
     IAAGAHFAAL ARDEVTFYTA PIKALVSEKF FELCKLFGTE NVGMLTGDAS VNADAPVICC
     TAEVLASIAL RDGKNADVGQ VVMDEFHFYA EGDRGWAWQI PLLELPQAQF ILMSATLGDV
     SFFEKDLTRR TSRPTSVVRS ATRPVPLSYE YQFTPLTETL TDLLQSRQAP VYIVHFTQAQ
     AVERAQALMS INMCSREEKD QIAELIGNFR FTTKFGRNLS RYVRHGIGVH HAGMLPKYRR
     LVEKLAQAGL LKVICGTDTL GVGVNVPIRT VLFTALTKYD GSRVRTLRAR EFHQIAGRAG
     RAGFDTAGLV VAQAPEHVIE NEKALAKAGD DPKKRRKVVR KKAPEGFVGW TESTFQKLID
     SEPEPLTSRF RVTHTMLLSV IARPGNAFEA MRHLLEDNHE PRRQQLRHIR RAIAIYRSLL
     DGGIVEKLDK PDAEGRIVRL TVDLQQDFAL NQPLSTFALA SFELLDPESP SYALDMVSVV
     ESTLDDPRQI LVAQQNKARG EAVAAMKADG VEYEERMERL QDVTYPKPLE ELLFHAYNTY
     RKSHPWVGDH PLSPKSVIRD MYERALSFTE LVSYYELART EGIVLRYLAS AYKTLDHTIP
     DDLKSEDLQD LIEWLGEMVR QVDSSLLDEW EQLANPEEMT AEEAREKADE VKPVTTNARA
     FRVLVRNAMF RRVELAALDQ VEDLGELDAE AGWDAEAWGE AMDKYWDEYE DLGTGPDARG
     PKLLVIKEEP ENGLWRVRQI FDDPNGDHDW GISAEIDLAA SDAEGRAVVR VTDVGQL
//