GenomeNet

Database: UniProt
Entry: A0A124IW77_9BACL
LinkDB: A0A124IW77_9BACL
Original site: A0A124IW77_9BACL 
ID   A0A124IW77_9BACL        Unreviewed;       441 AA.
AC   A0A124IW77;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   05-JUL-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ATW55_00105 {ECO:0000313|EMBL:KUO96529.1};
OS   Acidibacillus ferrooxidans.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Acidibacillus.
OX   NCBI_TaxID=1765683 {ECO:0000313|EMBL:KUO96529.1, ECO:0000313|Proteomes:UP000053557};
RN   [1] {ECO:0000313|EMBL:KUO96529.1, ECO:0000313|Proteomes:UP000053557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ITV001 {ECO:0000313|EMBL:KUO96529.1,
RC   ECO:0000313|Proteomes:UP000053557};
RA   Dall'Agnol H., Nancucheo I., Johnson B., Oliveira R., Leite L.,
RA   Pylro V., Nunes G.L., Tzotzos G., Fernandes G.R., Dutra J.,
RA   Orellana S.C., Oliveira G.;
RT   "Draft genome sequence of Acidibacillus ferrooxidans ITV001, isolated
RT   from a chalcopyrite acid mine drainage site in Brazil.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUO96529.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LPVJ01000011; KUO96529.1; -; Genomic_DNA.
DR   RefSeq; WP_067713180.1; NZ_LPVJ01000011.1.
DR   EnsemblBacteria; KUO96529; KUO96529; ATW55_00105.
DR   Proteomes; UP000053557; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053557};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053557}.
FT   DOMAIN      133    265       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      346    415       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     141    148       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   441 AA;  50051 MW;  5EF9A88B4BEF3669 CRC64;
     MSNEGRTLWL KTLSELKKLE PFVHAALYGA DVDTFDGTNL QVAVPTPSIL DHMTKSGNDT
     RVEQIVSAFH GSPVRLQFIV KRFTENSTPK TARTVESKNP FNPHYTFETF VVGERNRLAH
     AASIAVAERP GRGYNPFFLH GDVGLGKTHL MHAIAQRALQ MNPTALITYI TTETFVREYV
     TALQFNHVDE FRRRYRNVDI LLIDDIQFIS GKDSTQEEFF HTFNTLYSEQ KQIVITSDRA
     PKEISDLEDR LRSRFSGGLI IDVKPPDLET RMAILRRKAR AEGVDIPDDA IQVIASHIET
     NVRELEGALI RVIAYSSMMN KDIDAALTQT AISDLIPENQ QNRSVTLTDI QKAVCTHFHI
     KMDDLRGRSR QKDIANPRQI AMYLTRELTD LSLPKIGHDF GGRDHTTVLH ACEKIDKLLS
     TDPEIKRTID HLKHTLTILT R
//
DBGET integrated database retrieval system