ID A0A125RD22_9EURY Unreviewed; 428 AA.
AC A0A125RD22;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0000313|EMBL:AMD17612.1};
DE EC=2.5.1.49 {ECO:0000313|EMBL:AMD17612.1};
GN ORFNames=TL18_06020 {ECO:0000313|EMBL:AMD17612.1};
OS Methanobrevibacter sp. YE315.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=1609968 {ECO:0000313|EMBL:AMD17612.1, ECO:0000313|Proteomes:UP000057992};
RN [1] {ECO:0000313|EMBL:AMD17612.1, ECO:0000313|Proteomes:UP000057992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YE315 {ECO:0000313|EMBL:AMD17612.1,
RC ECO:0000313|Proteomes:UP000057992};
RA Ouwerkerk D., Gilbert R.A., Klieve A.V., Martinez E.;
RT "Genome sequence of Methanobrevibacter sp. YE315.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077}.
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DR EMBL; CP010834; AMD17612.1; -; Genomic_DNA.
DR RefSeq; WP_067042861.1; NZ_CP010834.1.
DR AlphaFoldDB; A0A125RD22; -.
DR STRING; 1609968.TL18_06020; -.
DR GeneID; 28487398; -.
DR KEGG; meye:TL18_06020; -.
DR PATRIC; fig|1609968.3.peg.1241; -.
DR OrthoDB; 43458at2157; -.
DR Proteomes; UP000057992; Chromosome.
DR GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transferase {ECO:0000313|EMBL:AMD17612.1}.
SQ SEQUENCE 428 AA; 46104 MW; 9981D81E672F3AF9 CRC64;
MAYEIKNKKN ISTIGVHAGQ EEVDETGSRV TPIYQTTSYV FESSEQAANR FALKEGGNIY
TRLTNPTTEA FEKRMAAIEG GTAAYATASG MSAIFYAIIN LTQVGDNIVS ADNLYGGTYE
LFENTLEELG RTVTFVDSQS PELFEEAIDD KTKAIYVESI GNPKLDIPDF DKLAEIAHSH
QIPLIADNTV GIGSVRPFDH GADIIASSAT KYIGGHGTTL GGIVIEKGDF DWMNGKFPTL
SEPDPTYNGL VFAETFKGSA FTTRIRAVIG RDTGAVPSPF GSFLLLQGLE TLGLRIERHA
SNAMAVAEHL EAHPKVAWVT YSGLESSPNH EVAKKYAEKG YGGIVSFGLK AGYEGALKFI
ESVELLSFLA NIGDAKSLVT HPASTTHSQL SAEQQLSTGV TPDLIRFSVG IEDIEDILAD
VDQALEKI
//
