ID A0A126RKA5_9SPHN Unreviewed; 772 AA.
AC A0A126RKA5;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:AMK22466.1};
GN ORFNames=K426_07595 {ECO:0000313|EMBL:AMK22466.1};
OS Sphingobium sp. TKS.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1315974 {ECO:0000313|EMBL:AMK22466.1, ECO:0000313|Proteomes:UP000060779};
RN [1] {ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|Proteomes:UP000060779};
RA Tabata M.;
RT "Whole genome sequence of gamma-HCH degrading bacterium Sphingobium sp.
RT TKS.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AMK22466.1, ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|EMBL:AMK22466.1,
RC ECO:0000313|Proteomes:UP000060779};
RX PubMed=27056231;
RA Tabata M., Ohhata S., Kawasumi T., Nikawadori Y., Kishida K., Sato T.,
RA Ohtsubo Y., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of a gamma-Hexachlorocyclohexane Degrader,
RT Sphingobium sp. Strain TKS, Isolated from a gamma-Hexachlorocyclohexane-
RT Degrading Microbial Community.";
RL Genome Announc. 4:0-0(2016).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP005083; AMK22466.1; -; Genomic_DNA.
DR RefSeq; WP_066555647.1; NZ_CP005083.1.
DR AlphaFoldDB; A0A126RKA5; -.
DR STRING; 1315974.K426_07595; -.
DR KEGG; spht:K426_07595; -.
DR PATRIC; fig|1315974.3.peg.1588; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000060779; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:AMK22466.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:AMK22466.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000060779};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 147..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 85086 MW; AF0CE2258A964873 CRC64;
MPSFAPALET TLHNALTHAS ERRHEYATLE HLLLALIDDE HASKVMQACG VELGELSDAV
TQYLDSELDS LKVEGASDPS PTSGFQRVVQ RAILHVQSSG KDEVTGANVL VALFSERESY
AVYFLQQQDM SRLDAVSYIS HGVGKGTAIP EQRETKGAQE EEKKVQDSKG KKDSALEQFT
VNLNEKAARG KVDPLIGRAS EVDRTIQILC RRSKNNPLYV GDPGVGKTAI AEGLARKIVE
GEVPDVLKEA VIYSLDMGAL LAGTRYRGDF EERLKAVVTE LEKMPHAVLF IDEIHTVIGA
GATSGGAMDA SNLLKPALSG GTIRCIGSTT YKEFRNHFEK DRALLRRFQK IDVNEPTIED
TIKILAGLRS AFEEHHNVKY TPDAIKAAVE LSARYINDRK LPDKAIDVID EVGAMQMLVV
PSKRKKTITP KEIEQVIATM ARIPPKTVSA DDKSVLETLD TDLKRVVFGQ NRAIEVLSSA
IKLSRAGLRD PDKPIGNYLF SGPTGVGKTE VARQLAHLLG IPLQRFDMSE YMERHSVSRL
IGAPPGYVGY DQGGLLTDAV DQNPHCVLLL DEVEKAHPDL FNILLQVMDN GRLTDHHGKS
VDFRNTILIM TTNAGASDMA KESIGFGEFT REDVQEDAVK KLFTPEFRNR LDAIVPFGYL
PPEIVARVID KFVLQLELQL ADRDVHITLD DEAKAWLTKR GYDKLYGARP MGRLMQEKIK
QPLAEELLFG KLVHGGEVHV RLKDDALAFE ITPAAPKKGK KGSKAKPAES TK
//
