ID A0A126RLS8_9SPHN Unreviewed; 796 AA.
AC A0A126RLS8;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN ORFNames=K426_11250 {ECO:0000313|EMBL:AMK23188.1};
OS Sphingobium sp. TKS.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1315974 {ECO:0000313|EMBL:AMK23188.1, ECO:0000313|Proteomes:UP000060779};
RN [1] {ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|Proteomes:UP000060779};
RA Tabata M.;
RT "Whole genome sequence of gamma-HCH degrading bacterium Sphingobium sp.
RT TKS.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AMK23188.1, ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|EMBL:AMK23188.1,
RC ECO:0000313|Proteomes:UP000060779};
RX PubMed=27056231;
RA Tabata M., Ohhata S., Kawasumi T., Nikawadori Y., Kishida K., Sato T.,
RA Ohtsubo Y., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of a gamma-Hexachlorocyclohexane Degrader,
RT Sphingobium sp. Strain TKS, Isolated from a gamma-Hexachlorocyclohexane-
RT Degrading Microbial Community.";
RL Genome Announc. 4:0-0(2016).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964,
CC ECO:0000256|HAMAP-Rule:MF_01403};
CC -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC ECO:0000256|HAMAP-Rule:MF_01403}.
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DR EMBL; CP005083; AMK23188.1; -; Genomic_DNA.
DR RefSeq; WP_066556931.1; NZ_CP005083.1.
DR AlphaFoldDB; A0A126RLS8; -.
DR STRING; 1315974.K426_11250; -.
DR KEGG; spht:K426_11250; -.
DR PATRIC; fig|1315974.3.peg.2367; -.
DR OrthoDB; 9768449at2; -.
DR Proteomes; UP000060779; Chromosome 1.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR HAMAP; MF_01403; Phosphoketolase; 1.
DR InterPro; IPR023962; Phosphoketolase.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR Pfam; PF03894; XFP; 1.
DR Pfam; PF09363; XFP_C; 1.
DR Pfam; PF09364; XFP_N; 1.
DR PIRSF; PIRSF017245; Phosphoketolase; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW Reference proteome {ECO:0000313|Proteomes:UP000060779};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052, ECO:0000256|HAMAP-
KW Rule:MF_01403}.
FT DOMAIN 19..379
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09364"
FT DOMAIN 594..794
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09363"
SQ SEQUENCE 796 AA; 88832 MW; F6CC98E8DA5BF700 CRC64;
MTHDTDVRHG SFDPAAPLDA DELKRMDAWW RAANYLNVGQ IYLSANPLLR EALKIEHIKP
RLLGHWGTSP GLNLVYVHMN RLIRKYDLDT IYMAGPGHGG PALIANVWLE GSYSDFYPEI
TRDGAGMLRL FRQFSTPGGV PSHVSVPTPG SIHEGGELGY VLLHAFGAVM DNPDLLVTAV
VGDGEAETGP LAGSWKSIDF LNPTRDGAVL PILHLNGYKI SGPTVWARHS DADLAKFFEG
QGYAPVFVEG DDPMVVHQQF AAVLEAAVLG IRDIQKEARA NGLGDRPVWP LIVLRTPKGW
TGPKIVDGVQ IEGTFRAHQV PVSEVRTNPE HLRILEDWLR SYHPEELFDA DGRLQPEIAA
LAPEGDRRMG SNPQANGGLL TKPLKLPVYT VYQVRFERRA AERIGSTAVL GQYLRDLYRD
NPDNFRLFCP DETNSNRLGA VFDASDRCLV SEIEPGDDHI SHGGRVMEVL SEHCCHGWLE
GYTLTGRHGL FATYEAFAMI IDSMAMQHSK WIEHARRVPW RADIPSLNYL LTSTCWRNDH
NGFSHQGPGF IDTIIHRKPV VARVYLPPDA NCLLSVADHC LRSRNYLNLI VIDKQPQLQW
LTMAEAEAHC ASGAGVWDMY SNQPEAPDIV LACAGDVPTQ ETIAAAWMLR RHAPDLKVRV
VNIVDLMRLA PADRHPHGMS DADFVEIFTA NVPVVFAFHG YPGVVHDLLH GRSAHERFHV
RGYMEEGTTT TPFDMVVLNE MSRLHLCLDA LRYVSGALTA NSDLIERCNA LLAEHEAYIR
EHFDDLPEIR DWTWSD
//
