ID A0A126ZA95_9BURK Unreviewed; 560 AA.
AC A0A126ZA95;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AX767_03535 {ECO:0000313|EMBL:AMM23524.1};
OS Variovorax sp. PAMC 28711.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1795631 {ECO:0000313|EMBL:AMM23524.1, ECO:0000313|Proteomes:UP000070169};
RN [1] {ECO:0000313|EMBL:AMM23524.1, ECO:0000313|Proteomes:UP000070169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 28711 {ECO:0000313|EMBL:AMM23524.1,
RC ECO:0000313|Proteomes:UP000070169};
RA Park H.;
RT "Complete genome of Variovorax sp.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP014517; AMM23524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A126ZA95; -.
DR STRING; 1795631.AX767_03535; -.
DR KEGG; vaa:AX767_03535; -.
DR Proteomes; UP000070169; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AMM23524.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000070169};
KW Transferase {ECO:0000313|EMBL:AMM23524.1}.
FT DOMAIN 29..84
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 102..154
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 151..199
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 224..278
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 303..521
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 526..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 269..296
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 560 AA; 61162 MW; 7FE7AF5B13D2ACFD CRC64;
MPPKLPSDVL RQAAALQDAI FNSEMFSKIA TDADGVIQIF NVGAQRMLGY SAAEVINRIT
PADISDPAEL VARARALSEE LATPIAPGFE ALVFKSCRGI EDIYELTCIR KDGSRLPVVV
SVTALRDPAD AVIGYLLIAT DNSARKQAEA AKREHDALLQ TIHLHSIVSV TDRSGRIIEV
NDGFCRISGY SRAELLGQTH GIVNSGVQKE AFWIDMWRSI TAGRPWRGEI CNRAKDGSLY
WVDSVIAPFL DDAGKTKNYI SIRTDVTDRK EAEAARQTLN EHLAAAMQAA EKANQAKSDF
LSSMSHELRS PLNAILGFAQ LLDSGTPAPT PSQKESIDQV LLAGWYLLAL INEILDLSLI
ESGKLSLSPE SMALADVLND CQAMIEPQAR KGSITLVFPA FDAPHFVKAD RTRVKQVFVN
LLSNAIKYNR PGGAVMVDCH DTGAGRVRVT FKDTGEGLSQ DKLAQLFEPF NRLGQEAGPE
EGTGIGLVVS KRLIELMGGT IGVASTVGVG TTFWIELQRP ARRNSIRGSH DWDRRRPHPP
TRRHRDRPCS ASKTTRPTCC
//
