ID A0A127VCW3_9SPHI Unreviewed; 299 AA.
AC A0A127VCW3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:AMP99134.1};
GN ORFNames=AY601_2239 {ECO:0000313|EMBL:AMP99134.1};
OS Pedobacter cryoconitis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=188932 {ECO:0000313|EMBL:AMP99134.1, ECO:0000313|Proteomes:UP000071561};
RN [1] {ECO:0000313|EMBL:AMP99134.1, ECO:0000313|Proteomes:UP000071561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27485 {ECO:0000313|EMBL:AMP99134.1,
RC ECO:0000313|Proteomes:UP000071561};
RA Lee J., Kim O.-S.;
RT "Complete genome sequence of Pedobacter cryoconitis PAMC 27485.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP014504; AMP99134.1; -; Genomic_DNA.
DR RefSeq; WP_068400650.1; NZ_CP014504.1.
DR AlphaFoldDB; A0A127VCW3; -.
DR KEGG; pcm:AY601_2239; -.
DR PATRIC; fig|188932.3.peg.2344; -.
DR OrthoDB; 9778880at2; -.
DR Proteomes; UP000071561; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000071561}.
FT ACT_SITE 137
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 165
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 49
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 299 AA; 32594 MW; BA2842CE4C1F02A2 CRC64;
MKKAPFKGVV AYPVTPFDNN ESIDIPLFKK HVERLVSAGS HGIAPLGSTG VMPYLTDAEK
EAMTEATIQQ VANRVPILVG VSNLTTEKTV YHSQFAEKAG ATAVMISPMS YWKLTDDEIV
KHYDTVASKI SIPIMAYNNP ATAGVDMSPA LLKRLLQIPN VTMIKESTGD IQRMHYLRKE
LGEEVTFFNG SNPLALAAFS AGATGWCTAA ANLIPELNIA LYDAVQENDL DQARRLFYKQ
VDLLKFIVAK GLPRAIKTGL DLLGIDGGGF KSPLKPLTEN ETSELDGILS AIKSEIYQY
//
