ID A0A127VUP2_SPOPS Unreviewed; 303 AA.
AC A0A127VUP2;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=DNA-3-methyladenine glycosylase II {ECO:0000256|ARBA:ARBA00012000};
DE EC=3.2.2.21 {ECO:0000256|ARBA:ARBA00012000};
GN ORFNames=AZE41_03075 {ECO:0000313|EMBL:AMQ05024.1};
OS Sporosarcina psychrophila (Bacillus psychrophilus).
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Sporosarcina.
OX NCBI_TaxID=1476 {ECO:0000313|EMBL:AMQ05024.1, ECO:0000313|Proteomes:UP000071057};
RN [1] {ECO:0000313|EMBL:AMQ05024.1, ECO:0000313|Proteomes:UP000071057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6497 {ECO:0000313|EMBL:AMQ05024.1,
RC ECO:0000313|Proteomes:UP000071057};
RA Yan W.;
RT "Complete genome sequence of the Sporosarcina psychrophila DSM6497, a
RT psychrophila Bacillus that can mediate the Ca2+ precipitation.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-
CC methylguanine, 7-methylguanine and 7-methyladenine.; EC=3.2.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000086};
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DR EMBL; CP014616; AMQ05024.1; -; Genomic_DNA.
DR RefSeq; WP_067205513.1; NZ_CP014616.1.
DR AlphaFoldDB; A0A127VUP2; -.
DR STRING; 1476.AZE41_03075; -.
DR KEGG; spsy:AZE41_03075; -.
DR OrthoDB; 9785929at2; -.
DR Proteomes; UP000071057; Chromosome.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0008534; F:oxidized purine nucleobase lesion DNA N-glycosylase activity; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR023170; HhH_base_excis_C.
DR InterPro; IPR012904; OGG_N.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF12; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR Pfam; PF07934; OGG_N; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
FT DOMAIN 138..303
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
SQ SEQUENCE 303 AA; 35124 MW; 0F7EC36D6273EDD1 CRC64;
MLVNQQDHLI IAVPKEFNFK ENISYMSRSN NECMFEIRDG KVIKAIPVGN EILLVEVSEN
TEGNLLVRFI EKYTPSNDSV RDMVVHYVRD WFDLDTDLKP YYEMAKRDPL LQQAVSEFYG
LRNIGIPDLF EALCWGILGQ QINLTYAYTL KRRFVETFGN SIEWEGQSYW IFPEPEYIAK
LTVEDLSSLK MTVKKCEYLI GVAQLIADGS LSKAQVLETG NFKEAENMLI KIRGIGPWTA
NYVLMRCLRF PNAFPIADVG LHNAIKHLTG AEEKPTKEEI LKLAAPWENW ESYATFYLWR
FLY
//
