ID   A0A131ZWD0_SARSC        Unreviewed;      1252 AA.
AC   A0A131ZWD0;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Lipase-like protein 1 {ECO:0000313|EMBL:KPM03142.1};
GN   ORFNames=QR98_0015720 {ECO:0000313|EMBL:KPM03142.1};
OS   Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC   Sarcoptidae; Sarcoptinae; Sarcoptes.
OX   NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM03142.1, ECO:0000313|Proteomes:UP000616769};
RN   [1] {ECO:0000313|EMBL:KPM03142.1, ECO:0000313|Proteomes:UP000616769}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM03142.1};
RX   PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA   Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT   "Draft genome of the scabies mite.";
RL   Parasit. Vectors 8:585-585(2015).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPM03142.1}.
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DR   EMBL; JXLN01004210; KPM03142.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A131ZWD0; -.
DR   VEuPathDB; VectorBase:SSCA007674; -.
DR   OrthoDB; 3091216at2759; -.
DR   Proteomes; UP000616769; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 3.
DR   Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase.
DR   InterPro; IPR001024; PLAT/LH2_dom.
DR   InterPro; IPR036392; PLAT/LH2_dom_sf.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610:SF178; FI22312P1; 1.
DR   PANTHER; PTHR11610; LIPASE; 1.
DR   Pfam; PF00151; Lipase; 2.
DR   Pfam; PF01477; PLAT; 1.
DR   PRINTS; PR00821; TAGLIPASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 3.
DR   SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          1..329
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
FT   DOMAIN          353..453
FT                   /note="PLAT"
FT                   /evidence="ECO:0000259|Pfam:PF01477"
FT   DOMAIN          789..1097
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KPM03142.1"
SQ   SEQUENCE   1252 AA;  141094 MW;  83F4132099059836 CRC64;
     SVCYGEYGCF NKTELSNEIK IANLASKLPE SPEEQDVHFY FFSCRNRLNP IRKRFNVEEK
     DLRDIGFDPN NQTIVMVHGY TDFYNEFNWM GDLKDSILNT QNCKSNLIIV DWSFGAKAPY
     SQAVANTRVV GSIIAVLIQK LNNVYKTSNN DFIILGHSLG GQIVGFAGKR INNPKVRLII
     GLDPAGPAFN NVTESNHLTP NDGQLVVTVH TNGAANIVDG LGIDKPLGHY SFFPNGGSVQ
     PGCEPAKGVA SVLAKGLGEG VADAFACSHR KAQEFAIYDD EKYAHYESLG YNCKDYDHFQ
     RGHCTKCSSA LQCNRWGRWF DYWPNQSRPK NWTKPIVLYI NTVGKYPFSL FHYGIKVITS
     SDDFASFKGQ LSMNLTGTIR KTFHVTINLE DQFEPNSYYT HLFTLRKSLG KIVEIKAKLL
     DKNLKELSTK DVWIVVERIE VTFMNGHQQS LAHKTPEKNE ATNPLDLDQS RLTSRKFFKD
     HNEEIVCYSP YGCFTKNEVD NKFTIGKILA RFPEDPRKLG VQYYFFSCKD YFNPTVLPWT
     LNESDLIRNL NYNPKFQTII LVHGYTERFN QLDWTGDLKD TVLNRDSCRW NVIGVEYGRA
     VQSPYAQAIA NAKLVGAMIA YLIRQLNLAF NTTNNDFVLV GHSLGCHTAG FAGKKLTDPK
     LRMILASEPA GPAFNRVSNS ERLSPTDADL VLTVQTNQGS SFLQGSGVKD PLGHYSFLVN
     DASAQPGCQV INRMGNLFTD GLINGLYAIG GCSHARSIEL IIAYAYEDSR NDFQVMAYRC
     PRYQDYDEEV CYEGYGCFNQ SEINEDHPLA SDLVASLPES PNSYVLQLFF FTCENPLNPT
     IFNQNVTVDE LKRSANFNPN RRTVLIVHGR NEHYDEFLWT GDMKDLLVTR DGCEYNVISI
     DYYRMTDHSY SSGVANTQVV GAVLAKLIEK LSQAFKVDAL DFICAGHSLG SHVCGFTGQR
     LKSSQLGMIL GMDPAGPAFS NVHPRSRLSI DDAKLVVTIH TNAADNVIEG YGSFEPMGHY
     NFFVNGGSTQ PGCDKITAKF VCSHQKSTQY AIYNETLFDN YESMGYRCPN YDDFEKGKCN
     RCEEPEDCAR FGYWFTYWPH QEVGPDFTEP LIYYVDAKEK LPYSLYHYSV ILSIDAESPT
     FNGRLALNLS GSIRSFYIEK HDLEAKFEAN QTYSFLMKEK KSLGRIEKIS ATISSSAGLS
     FFDPHSSVDV KQIEVRYMNG FDQSTRDDLS SILTPEQSST IRSNQTTSFV YK
//