ID A0A132A5J4_SARSC Unreviewed; 614 AA.
AC A0A132A5J4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Transcriptional coactivator YAP1 {ECO:0000313|EMBL:KAF7489953.1};
DE SubName: Full=Yorkie-like protein {ECO:0000313|EMBL:KPM06232.1};
GN ORFNames=QR98_0047060 {ECO:0000313|EMBL:KPM06232.1}, SSS_8759
GN {ECO:0000313|EMBL:KAF7489953.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM06232.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM06232.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM06232.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
RN [2] {ECO:0000313|Proteomes:UP000070412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33001992;
RA Korhonen P.K., Gasser R.B., Ma G., Wang T., Stroehlein A.J., Young N.D.,
RA Ang C.S., Fernando D.D., Lu H.C., Taylor S., Reynolds S.L., Mofiz E.,
RA Najaraj S.H., Gowda H., Madugundu A., Renuse S., Holt D., Pandey A.,
RA Papenfuss A.T., Fischer K.;
RT "High-quality nuclear genome for Sarcoptes scabiei-A critical resource for
RT a neglected parasite.";
RL PLoS Negl. Trop. Dis. 14:0-0(2020).
RN [3] {ECO:0000313|EMBL:KAF7489953.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SSS_KF_BRIS2020 {ECO:0000313|EMBL:KAF7489953.1};
RA Korhonen P.K.K., Guangxu M.G., Wang T.W., Stroehlein A.J.S., Young N.D.,
RA Ang C.-S.A., Fernando D.W.F., Lu H.L., Taylor S.T., Ehtesham M.E.M.,
RA Najaraj S.H.N., Harsha G.H.G., Madugundu A.M., Renuse S.R., Holt D.H.,
RA Pandey A.P., Papenfuss A.P., Gasser R.B.G., Fischer K.F.;
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblMetazoa:KAF7489953.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; WVUK01000063; KAF7489953.1; -; Genomic_DNA.
DR EMBL; JXLN01010712; KPM06232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132A5J4; -.
DR EnsemblMetazoa; SSS_8759s_mrna; KAF7489953.1; SSS_8759.
DR VEuPathDB; VectorBase:SSCA010042; -.
DR OMA; LPMRMRN; -.
DR OrthoDB; 2593247at2759; -.
DR Proteomes; UP000070412; Unassembled WGS sequence.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 6.20.430.10; -; 1.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR17616:SF8; YES-ASSOCIATED PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000070412}.
FT DOMAIN 188..221
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 314..347
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 57..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 67288 MW; C37C8729C6FEEA1D CRC64;
MHLKSESESN NTDHHNNGNA IVRVESAAGL DELFKAIMSP NDGQSRLPHQ VPMRQRRLPP
SFFRPPSASS SNNSLASASH SRESSLDGGY QSGQTPVNTP NNGQAKQNNV TVLNYSGANN
GMIIHPRANS SPAALQPANE SVNNLSSSGG QSFNSNEVLA KPSNESATIN SAPLTTHFRQ
MSYDLNQIRL PDGWEMSFTA SGERYFLNHK EKTTTWEDPR KKIVEEMLHH NNSSSKQLPS
INSLHPQNVG SLSSASNMQP QQQQQQSSAI QTSVQNGLSQ QQNSSGSITS TPLPASNSTH
VVHEHLSYID PTLVPLPNGW EQAQTNTGDI YFISHIDQTT TWFHPSIPRN LQMKRIQQQT
CSIQPPPFQT NGAKNASTIN NNAMNIPPEL VVALKNMNTS CQQQQTSASI TASSIMPPVA
SMVTNPLEMS MQKTPQNQHL RDLELERERM KQRQEELLQS SLLNSSASNN LLSVSNDQAT
SSPFMLQNEC HSRQDSIDSG LDLGNSSGFS STPLLTIDSN MFRLTNNPTS STTTTPAQTN
FLPTVISNQT VSSNTANTNN APLSDEMMAF ENMQISGLDL DSESMDFMQG LDIDLLSNVE
ELLNSNKDNI MTWL
//
