ID A0A132C1C3_9RHOB Unreviewed; 805 AA.
AC A0A132C1C3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=4-methylaminobutanoate oxidase (Formaldehyde-forming) {ECO:0000313|EMBL:KUP93927.1};
DE EC=1.5.3.19 {ECO:0000313|EMBL:KUP93927.1};
GN Name=mlr_1 {ECO:0000313|EMBL:KUP93927.1};
GN ORFNames=TRIHO_12480 {ECO:0000313|EMBL:KUP93927.1};
OS Tritonibacter horizontis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Tritonibacter.
OX NCBI_TaxID=1768241 {ECO:0000313|EMBL:KUP93927.1, ECO:0000313|Proteomes:UP000068382};
RN [1] {ECO:0000313|EMBL:KUP93927.1, ECO:0000313|Proteomes:UP000068382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O3.65 {ECO:0000313|EMBL:KUP93927.1,
RC ECO:0000313|Proteomes:UP000068382};
RA Poehlein A., Giebel H.A., Voget S., Brinkhoff T.;
RT "Genome sequence of the marine Rhodobacteraceae strain O3.65, Candidatus
RT Tritonibacter horizontis.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUP93927.1}.
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DR EMBL; LPUY01000040; KUP93927.1; -; Genomic_DNA.
DR RefSeq; WP_068241357.1; NZ_LPUY01000040.1.
DR AlphaFoldDB; A0A132C1C3; -.
DR PATRIC; fig|1768241.3.peg.1307; -.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000068382; Unassembled WGS sequence.
DR GO; GO:0102317; F:4-methylaminobutyrate oxidase (demethylating) activity; IEA:UniProtKB-EC.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KUP93927.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000068382}.
FT DOMAIN 6..367
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 370..423
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 427..692
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 718..797
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 805 AA; 88612 MW; 4EA2D7FC518F647A CRC64;
MKTTTRVAVI GGGVVGCSVL YHLTKLGWSD VMLIERSELT SGSTWHAAGG FHTLNGDTNM
AALQGYTIKL YKELEAITGM SCGLHHVGGV TLADTQERFD MLKAERAKHR FMGLETEIVS
PEEIKKIAPV TNIDGIVGGL YDPLDGHLDP SGTTHAYAKA ARMGGATIET HCKVIETNQR
PDGTWDVVTN KGTIHAEHIV NAGGLWAREV GAMAGIYFPL HPMEHQYIVT DEVPMVAEII
DGGGEHPHVM DPAGESYLRQ EGRGLCIGFY EQPCRPWAVD GTPWDFGHEL LPDDFDKIEE
SIEFAYKRFP ALAEAGVKSV IHGPFTFAPD GNPLVGPVPG VRNYWSACAV MAGFSQGGGV
GLMLAQWMVE GECERDTAAM DVARFGTWIT PGYTRPKVVE NYQKRFSIAY PNEELPAARP
FRTTPMYDIF DSMGAVWGHQ YGTEIPNYFA AEGEARYETP SFRRSNAFDA TAREVKAVRE
AVGINEIHNF GKYRVKGAGA RAWLDRIMAG RVPQQGRLSL TPMLSPKGRL IGDFTISCLA
EDDFQLTASY GAQAYHMRWF LQNRDAGVTI DNVSDQVNGF QIAGPKAREV LQACTRSDIS
DMRFLDVRRL TVGMVDCLVQ RVSYTGDLGY EIYCDLPSQR ALWTSLWGAG QSHGMKPFGM
RAMMSLRLDK FFGSWLSEFS PDYTAAETGL DRFISFKKPV DFIGRSAAEA ERVTGVNRKL
CAFEVSAEDA DVVAYEPIWL DGDVVGFCTS GGYSHYAQKS IALGFLPVDR IADGLEVEIE
ILGKRHAARL LAEPLFDTDG TRMRG
//
