ID A0A133YH51_9FIRM Unreviewed; 383 AA.
AC A0A133YH51;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Lactaldehyde reductase {ECO:0000313|EMBL:KXB42506.1};
GN ORFNames=HMPREF1872_00182 {ECO:0000313|EMBL:KXB42506.1};
OS Amygdalobacter nucleatus.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Amygdalobacter.
OX NCBI_TaxID=3029274 {ECO:0000313|EMBL:KXB42506.1, ECO:0000313|Proteomes:UP000070080};
RN [1] {ECO:0000313|Proteomes:UP000070080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA00274 {ECO:0000313|Proteomes:UP000070080};
RA Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB42506.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSCV01000002; KXB42506.1; -; Genomic_DNA.
DR RefSeq; WP_066712562.1; NZ_KQ959565.1.
DR AlphaFoldDB; A0A133YH51; -.
DR STRING; 1497955.HMPREF1872_00182; -.
DR PATRIC; fig|1497955.3.peg.177; -.
DR OrthoDB; 9804734at2; -.
DR Proteomes; UP000070080; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd08176; LPO; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR InterPro; IPR013460; Lactal_redase.
DR NCBIfam; TIGR02638; lactal_redase; 1.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
DR PROSITE; PS00060; ADH_IRON_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000070080}.
FT DOMAIN 11..373
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 383 AA; 41321 MW; AC8F012F11AB5AA4 CRC64;
MVHKITLNAT SYHGAGAIQE IMTEIKQHGF KKAFVCTDHD LVKFKVATKV TDLLDAAKFP
YEVYTDIKAN PTVENVQSGV AAFKASQADF ILAIGGGSSM DTAKAIAIII TNPEFADVRS
LEGLSPTKNP CAPIIAVPTT AGTAAEVTIN YVITDVQKAR KFVCVDPHDM PIVAVVDPEM
MASMPRNLAV ATGMDAMTHA IEGYTTKAAW EMTDMFHLEA IRLLSNNFRK AADGDMEAKA
GMALGQYIAG MGFSNVGLGI AHSMAHTLSA HYDTPHGIAC ALFLPIAMEF NSEYTGERLR
EVARALGVEG VDEMTQAEYR QAAINAVKKL EADLGVPTTL DKIKEEDLEQ LATDALNDAC
YPGNPRSATK EQVIAMFRKL MVK
//
