ID   A0A133YZ90_9ACTN        Unreviewed;       525 AA.
AC   A0A133YZ90;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   13-SEP-2023, entry version 27.
DE   RecName: Full=HTH OST-type domain-containing protein {ECO:0000259|PROSITE:PS51644};
GN   ORFNames=HMPREF3190_01485 {ECO:0000313|EMBL:KXB48503.1};
OS   Coriobacteriales bacterium DNF00809.
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales.
OX   NCBI_TaxID=1588753 {ECO:0000313|EMBL:KXB48503.1, ECO:0000313|Proteomes:UP000070490};
RN   [1] {ECO:0000313|Proteomes:UP000070490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DNF00809 {ECO:0000313|Proteomes:UP000070490};
RA   Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA   O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA   Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXB48503.1}.
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DR   EMBL; LSCX01000064; KXB48503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A133YZ90; -.
DR   STRING; 1588753.HMPREF3190_01485; -.
DR   PATRIC; fig|1588753.3.peg.1452; -.
DR   OrthoDB; 2379772at2; -.
DR   Proteomes; UP000070490; Unassembled WGS sequence.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   CDD; cd10146; LabA_like_C; 1.
DR   CDD; cd11297; PIN_LabA-like_N_1; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 3.30.420.610; LOTUS domain-like; 2.
DR   InterPro; IPR041966; LOTUS-like.
DR   InterPro; IPR021139; NYN.
DR   InterPro; IPR025605; OST-HTH/LOTUS_dom.
DR   PANTHER; PTHR35811:SF1; HTH OST-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR35811; SLR1870 PROTEIN; 1.
DR   Pfam; PF01936; NYN; 1.
DR   Pfam; PF12872; OST-HTH; 2.
DR   PROSITE; PS51644; HTH_OST; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000070490}.
FT   DOMAIN          174..247
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   DOMAIN          450..522
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   REGION          271..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..297
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..364
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..407
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..438
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   525 AA;  57473 MW;  774103CCF6B6035E CRC64;
     MEQKNSSDKR FALLIDADNV SSKYIGVILD ELSNYGIITY KRIYGDWTST LHAKWKDTLL
     ENSITPIQQF SYTTGKNATD SALIIDAMDI MYTKTVDGFC LVSSDSDFTR LAARIREAGL
     MVIGAGENKT PLPFRTACDV FKCLEVLLGE DDNKNDAAKQ KNGHNTQNAE LLLSRKKIEK
     TIIDIVTNNL NKERETGLGE IGSRLVKRYP DFDVRNYGTN QLSKLLAEFS SIKLVSSGKT
     MLVELADTHS NKQHHTQAAT KLKLVATSNA RTVQTTTAHQ KQQAASNATS APKAPKPAHQ
     TQQRKEESAN AQHTTNAELK TSNESNENTS ASAHATRVTH TTNTTNDKQT NDTATSTSSA
     SRKAKAPALT HASKAKESHA KTSNNTSKVA RLSHTIDDSH QREARPQTNK ALPRAVAKTR
     STDTTLTHPN TTQQPSISAQ TPLQTAAFPS LDALSAHITT LIAEHKNATI SVPALGKLIR
     TSIPNFEPKA YSYSKLSDLL AHISTIELVH KNKSIFATIR ANNQE
//