ID A0A133Z071_9ACTN Unreviewed; 726 AA.
AC A0A133Z071;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:KXB48844.1};
GN ORFNames=HMPREF3190_01407 {ECO:0000313|EMBL:KXB48844.1};
OS Coriobacteriales bacterium DNF00809.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales.
OX NCBI_TaxID=1588753 {ECO:0000313|EMBL:KXB48844.1, ECO:0000313|Proteomes:UP000070490};
RN [1] {ECO:0000313|Proteomes:UP000070490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00809 {ECO:0000313|Proteomes:UP000070490};
RA Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB48844.1}.
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DR EMBL; LSCX01000054; KXB48844.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133Z071; -.
DR STRING; 1588753.HMPREF3190_01407; -.
DR PATRIC; fig|1588753.3.peg.1377; -.
DR Proteomes; UP000070490; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR001150; Gly_radical.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
DR PROSITE; PS51149; GLY_RADICAL_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW ProRule:PRU00493}; Reference proteome {ECO:0000313|Proteomes:UP000070490}.
FT DOMAIN 3..96
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT DOMAIN 602..726
FT /note="Glycine radical"
FT /evidence="ECO:0000259|PROSITE:PS51149"
FT MOD_RES 704
FT /note="Glycine radical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ SEQUENCE 726 AA; 83079 MW; 9FA31BC3C355FA07 CRC64;
MLMKIIKRNG AEVEFDLTKI VNAIQAANNE VPEQQRLSDR EIGFAAANVA DLCEKAGHTV
QVEEIQDMVE DEIMRLDHFE VARKYIIYRY VRSEERHKNT TDDTILALIE CNNEEVKQEN
SNKNPTISSV QRDYMAGEVS KDLTMRTLLD PDIVQAHKEG IIHFHDSDYF AQHMHNCDLV
NLEDMLQNGT VISDTLIEKP HSFSTACNIA TQIIAQVASS QYGGQSISLT HLAPFVQISR
ERIAGELRDE LRELGVETSH ENFTAAVEKR VREEIRRGVQ TIQYQVVTLM TTNGQAPFVT
VFMYLNEAKN EQEKKDLALI IEETLNQRFQ GVKNEKGVWI SPAFPKLIYV LEDDNIEEGQ
PYYYLTELAA KCSAKRLVPD YVSEKYMKKI KIDKNGEGHC YTPMGCRSFL TPYVNEEGKP
QYYGRFNQGV VTINLPDVAL SSGGDIDKFW EIFDERLELC HRALMARHNR LKGTRSDVAP
ILWQYGALAR LKKGEVIDKL LYGGYSTISL GYAGLQECVY YLTGKSHTDP EATPFALKIM
QHMNDKCESW KKAHNIDFSI YGTPLESTTY KFAKALQRRF GIIKNVTDHG YITNSYHVNV
REEISAYEKL AFESAFQSLS PGGAISYVEV PNMQDNLKAV ISVLQFIYDH IMYAELNTKS
DYCQECGYDG EIKIIEEDKK LIWECPQCGN RNQDKMNVTR RTCGYIGTQF WNQGRTEEIR
DRVLHL
//
