ID A0A135LVE1_PENPA Unreviewed; 550 AA.
AC A0A135LVE1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Regulator of nonsense-mediated decay, UPF3 {ECO:0000313|EMBL:KXG52925.1};
GN ORFNames=PGRI_081800 {ECO:0000313|EMBL:KXG52925.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG52925.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG52925.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG52925.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- SIMILARITY: Belongs to the RENT3 family.
CC {ECO:0000256|ARBA:ARBA00005991}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG52925.1}.
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DR EMBL; LHQR01000015; KXG52925.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LVE1; -.
DR STRING; 5078.A0A135LVE1; -.
DR OMA; DARNTLH; -.
DR OrthoDB; 77197at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd12455; RRM_like_Smg4_UPF3; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR039722; Upf3.
DR InterPro; IPR005120; UPF3_dom.
DR PANTHER; PTHR13112:SF0; FI21285P1; 1.
DR PANTHER; PTHR13112; UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF03467; Smg4_UPF3; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000070168};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 405..479
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 57438 MW; 3B5104B346B642AD CRC64;
MMPPSKTTAG LLPISAAATQ KSGAVAPAKK TPKPPAPRLK LLIRRLPPGL TQAELESALG
DKWKAGAGNV DWLQYKPGKV SKDPNKPSRP SRAYIHVVST ECVSSLSDAV RQASFQDARN
TLHDPVLLGP PSLEFAPYAK TPGSRSRKDA RQGTIDQDSD FIAFLESLTQ PITRPAAVDS
TADGEDKKKE SVMTTPLVQF IKDKKASKSK DGSGSKSKHG RPDKESKQEK VQAKKLLQRG
DKEMATTSSD KKPKGEKTSK DSVKATKQAA AANAKGGKSS TASNTAKDTT TFLERKRERG
SITVATKILQ RDLGLSTSGG RRRGKGGSTD TASPKNDSSR DSAIPPADLP KKETTRPPKS
ASSTANTPKP KDSDPSSRPD AAAPPATLPA KSTKGGKAKH PSTAKQAFLK HANPSQGVTE
ALLESAFTPF GAVTKVEIDK KKGFGYVDFA EPEALRKAIA ASPVSVAQSQ VVVLERKENP
GIEKSRKGRE GFAANKVKAP TEAAGSASAG GNPGGNAGSS RGSRGGRGSR NKGSKGSAGA
SEKAGGTEAK
//
