ID A0A135SX86_9PEZI Unreviewed; 1611 AA.
AC A0A135SX86;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Dicer-like protein 1 {ECO:0000256|ARBA:ARBA00020797};
GN ORFNames=CNYM01_03121 {ECO:0000313|EMBL:KXH40529.1};
OS Colletotrichum nymphaeae SA-01.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1460502 {ECO:0000313|EMBL:KXH40529.1, ECO:0000313|Proteomes:UP000070054};
RN [1] {ECO:0000313|EMBL:KXH40529.1, ECO:0000313|Proteomes:UP000070054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA-01 {ECO:0000313|EMBL:KXH40529.1,
RC ECO:0000313|Proteomes:UP000070054};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum nymphaeae SA-01.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC {ECO:0000256|PROSITE-ProRule:PRU00657}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH40529.1}.
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DR EMBL; JEMN01001314; KXH40529.1; -; Genomic_DNA.
DR Proteomes; UP000070054; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18034; DEXHc_dicer; 1.
DR CDD; cd00593; RIBOc; 2.
DR Gene3D; 3.30.160.380; Dicer dimerisation domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR038248; Dicer_dimer_sf.
DR InterPro; IPR005034; Dicer_dimerisation_dom.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950:SF62; DICER-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR Pfam; PF03368; Dicer_dimer; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF00636; Ribonuclease_3; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS51327; DICER_DSRBF; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Antiviral protein {ECO:0000256|ARBA:ARBA00022721};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
FT DOMAIN 168..350
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 484..666
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 683..773
FT /note="Dicer dsRNA-binding fold"
FT /evidence="ECO:0000259|PROSITE:PS51327"
FT DOMAIN 1124..1235
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1286..1471
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT REGION 17..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1611 AA; 182493 MW; 9AB98137757F7DE8 CRC64;
METSKRQRIG DWPLIDGLGK LCLTPLPSKP STPVERSHEQ PSTTGLGTIC PAIEISTNLP
SPSYSTATSS RHGPIVNTDD VEEQDQADED EEDDYRRWSV NPERPRKISE KKRQDHAKFQ
SWIESNQAKV LEAASKTKAP AQGSVAYLVK ESENRRIIQT PREYQIELFE RAKQKNIIAV
LDTGTGKTLI AALLLRHILE KEVEDRALGK PKRTAFFLVD KVSLVFQQHA VLECNLEHSV
ARYCGDMVDE MWSSEFWAKQ FEENMVVVCT AAILQKCLMH SYIRMDQINL LIFDEAHHTK
KNHPYARIIK DFYIKEPEKD KRPKILGMTA SPVDAQTNMK VATAQLECLL HSEIATVSEE
SLALNPNQRK ITEREIHYTP LVRSFESELV QKIQALVRRN QLFDKELQWT TTAMAELGPW
VADRFWKLYL TDNTIARLAN RTDINYSGFD GNGKHTAAVQ KLRDIVQSHN FKPPTLSLDD
VSSKVLRLWD ELKVRFSQPT DYRCIVFVEM RLTAVMLAEL FKQDGMDLPH LKPAALVGSQ
ASAGLGNMSF KEQLLTITKF RRGEVNCIFS TQVAEEGIDI PACNVVMRFD LYKSVIQYIQ
SKGRARQHDS EYLSFVEIGN GRHTRAVAQA TYDQSVLRRF CSALPEDKKI MGMDINASVM
QAELHYQTYT IKETGAKLTW MSSLEVLANF ASSLRQSSDE VSMPEYVVTN QGQSFIAEVH
LPPKSPILSI TGMPHKRKQA ARCSAAFELC KELIKKKYID LNLQPIFTKK LPAMRNARLA
ISANKRAEYK MRTKPELWSR VGAFDHLYVT VLALASPDAV GKESKPLLLL TREKLPDLPP
IPLFFGNDQQ SDAFAVCLPR PINISSADSE LLKSFTLRVF KDVFSKEYEA AIFDMPYFLA
PTTQSHSADH QHADAATLVD WDHLQATNDR EYLDWDDSTS DEFFTDKLVI DPYAGSRKLR
LRGVRKDLKP MDPVPEGVPD PGHRPWRDSA VEKNIKEYSV SLWMKSRLKR TWRDTQPVVE
AEVISLRRNL LDDFVEATNE ESKVCYVILE PLRVSTLPME TVVMAFTFPA IIHRMDQVMV
ALDLCKLLKL DIRPDLALEA VTKDSDNSDE HDAEKINFQG GMGNNYERLE FIGDTCLKMA
TTIALFTNNP DNNEFQYHVE RMLLISNRNL LNKAIDRNLQ EYVRSKSFNR RSWYPQGLRL
IRGKEGTVDA NHALADKSIA DVCEALIGAA HLTFSDSNNF DMAIRAVSAM VNDKNHRMTS
WADYYAGYKP PSWQTEPASA MYRDVVRQVK NKVGYDFKSP ALLRSAFKHP SCPHNVCSLP
NYQRLEFLGD ALLDMVCVDF LYHKFPSADP EWLTRHKSTM VSNRFLACLC VKLDLHKHIL
TAQASLLSQT QEFVAALRFA EESAREEALR EAVQNGALAD GKQGKEALVT KATGNATTAT
PVSYWQHVED APKYLSDMME AYIGAVFVDS GYDYGQVRAF FEAHVRPFFT DMSLYSDYAL
NHPVTNVSHM LRNDFGCDGW RLMTNEVVPP IEAGAGVITE TQVLCGIMIH GQVYFHATAA
SGRYAKVAVA KMAITKFTDM DREAFRKEFA CDCQDVEGEC GTQQVDPRLA A
//
