ID A0A135VEN1_9ARCH Unreviewed; 553 AA.
AC A0A135VEN1;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:KXH71071.1};
GN ORFNames=AM325_15305 {ECO:0000313|EMBL:KXH71071.1};
OS Candidatus Thorarchaeota archaeon SMTZ1-45.
OC Archaea; Asgard group; Candidatus Thorarchaeota.
OX NCBI_TaxID=1706444 {ECO:0000313|EMBL:KXH71071.1, ECO:0000313|Proteomes:UP000070149};
RN [1] {ECO:0000313|EMBL:KXH71071.1, ECO:0000313|Proteomes:UP000070149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SMTZ1-45 {ECO:0000313|EMBL:KXH71071.1};
RX PubMed=26824177;
RA Seitz K.W., Lazar C.S., Hinrichs K.U., Teske A.P., Baker B.J.;
RT "Genomic reconstruction of a novel, deeply branched sediment archaeal
RT phylum with pathways for acetogenesis and sulfur reduction.";
RL ISME J. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH71071.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LRSL01000102; KXH71071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135VEN1; -.
DR STRING; 1706444.AM325_15305; -.
DR Proteomes; UP000070149; Unassembled WGS sequence.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF67; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE (ALKK-3); 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 32..409
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 461..537
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 553 AA; 62072 MW; 18C8486B1C9BF2EC CRC64;
MDIVKGFPAT SNSSSQLNVH NIIKHAARNF GRQEIVDRKH DGVLFRYSYL DAYKRVQRLA
NSLNSLGVMV GDKIGVLAWN THRYFEIYFS IPGSGAVMVL MNPRFTSQEL SYVANHAGLK
LIFVDEDMLP IVETFAAECE TIQGYVILTD KELDDLETGL KPVYSYEECV RKVEPVYEWP
NIDETSASSA CYTTGTTGRP KGVYYSHRDV YLQAMMYALN AMMSVKECVF QIVPMFHVLG
WGTPYAATMA GAKLVFTGRY SLENLDELVQ VLVQEKVTMS NGVPSILRAL LNSLLNMDPL
PDLSGVRFLC GGSEPPLSMI KEYWETTRAE IIHTYGSTEA QAIVTLNLPK PWLDREFSSE
EMWEQKKKQG CVVVGLDAKV VDSNGKKLPH DGKSVGEILL RGPWVLGKYH DAPGSESQFT
EDGYFRTGDV GAIDSEGYLK LTDRLRDLIK SGGEWISSVD MENEIINHPA VLEGAVVGIA
HPKWEERPLA LVVLRKEFRT KVDKADIIEH LGKRFANWQL PDEVLFVEAI PKTSVGKIDK
KVIRADYSDI YTR
//
